Active Recombinant Full Length Human SYT1 Protein, C-Flag-tagged

• Cat.No.: SYT1-426HFL
• Product Overview: Recombinant Full Length Human SYT1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin-1 participates in triggering neurotransmitter release at the synapse.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: MS digestion standard
• Molecular Mass: 47.4 kDa
• AA Sequence: MVSESHHEALAAPPVTTVATVLPSN ATEPASPGEGKEDAFSKLKEKFMNE LHKIPLPPWALIAIAIVAVL LVLTCCFCICKKCLFKKKNKKKGKE KGGKNAINMKDVKDLGKTMKDQALK DDDAETGLTDGEEKEEPKEE EKLGKLQYSLDYDFQNNQLLVGIIQ AAELPALDMGGTSDPYVKVFLLPDK KKKFETKVHRKTLNPVFNEQ FTFKVPYSELGGKTLVMAVYDFDRF SKHDIIGEFKVPMNTVDFGHVTEEW RDLQSAEKEEQEKLGDICFS LRYVPTAGKLTVVILEAKNLKKMDV GGLSDPYVKIHLMQNGKRLKKKKTT IKKNTLNPYYNESFSFEVPF EQIQKVQVVVTVLDYDKIGKNDAIG KVFVGYNSTGAELRHWSDMLANPRR PIAQWHTLQVEEEVDAMLAV
  KKTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Secreted Protein, Transmembrane

Gene Information

• Gene Name: SYT1 synaptotagmin 1 [ Homo sapiens (human) ]
• Official Symbol: SYT1
• Synonyms: P65; SYT; BAGOS; SVP65
• Gene ID: 6857
• mRNA Refseq: NM_001135806.2
• Protein Refseq: NP_001129278.1
• MIM: 185605
• UniProt ID: P21579