Active Recombinant Full Length Human USP24 Protein, C-Flag-tagged

• Cat.No.: USP24-1162HFL
• Product Overview: Recombinant Full Length Human USP24 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP24 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Bio-activity: In vitro deubiquitination assay
• Molecular Mass: 294.2 kDa
• AA Sequence: MESEEEQHMTTLLCMGFSDPATIRK ALRLAKNDINEAVALLTNERPGLDY GGYEPMDSGGGPSPGPGGGP RGDGGGDGGGGGPSRGGSTGGGGGF DPPPAYHEVVDAEKNDENGNCSGEG IEFPTTNLYELESRVLTDHW SIPYKREESLGKCLLASTYLARLGL SESDENCRRFMDRCMPEAFKKLLTS SAVHKWGTEIHEGIYNMLML LIELVAERIKQDPIPTGLLGVLTMA FNPDNEYHFKNRMKVSQRNWAEVFG EGNMFAVSPVSTFQKEPHGW VVDLVNKFGELGGFAAIQAKLHSED IELGAVSALIQPLGVCAEYLNSSVV QPMLDPVILTTIQDVRSVEE KDLKDKRLVSIPELLSAVKLLCMRF QPDLVTIVDDLRLDILLRMLKSPHF SAKMNSLKEVTKLIEDSTLS KSVKNAIDTDRLLDWLVENSVLSIA LEGNIDQAQYCDRIKGIIELLGSKL SLDELTKIWKIQSGQSSTVI ENIHTIIAAAAVKFNSDQLNHLFVL IQKSWETESDRVRQKLLSLIGRIGR EARFETTSGKVLDVLWELAH LPTLPSSLIQQALEEHLTILSDAYA VKEAIKRSYIIKCIEDIKRPGEWSG LEKNKKDGFKSSQLNNPQFV WVVPALRQLHEITRSFIKQTYQKQD KSIIQDLKKNFEIVKLVTGSLIACH RLAAAVAGPGGLSGSTLVDG RYTYREYLEAHLKFLAFFLQEATLY LGWNRAKEIWECLVTGQDVCELDRE MCFEWFTKGQHDLESDVQQQ LFKEKILKLESYEITMNGFNLFKTF FENVNLCDHRLKRQGAQLYVEKLEL IGMDFIWKIAMESPDEEIAN EAIQLIINYSYINLNPRLKKDSVSL HKKFIADCYTRLEAASSALGGPTLT HAVTRATKMLTATAMPTVAT SVQSPYRSTKLVIIERLLLLAERYV ITIEDFYSVPRTILPHGASFHGHLL TLNVTYESTKDTFTVEAHSN ETIGSVRWKIAKQLCSPVDNIQIFT NDSLLTVNKDQKLLHQLGFSDEQIL TVKTSGSGTPSGSSADSSTS SSSSSSGVFSSSYAMEQEKSLPGVV MALVCNVFDMLYQLANLEEPRITLR VRKLLLLIPTDPAIQEALDQ LDSLGRKKTLLSESSSQSSKSPSLS SKQQHQPSASSILESLFRSFAPGMS TFRVLYNLEVLSSKLMPTAD DDMARSCAKSFCENFLKAGGLSLVV NVMQRDSIPSEVDYETRQGVYSICL QLARFLLVGQTMPTLLDEDL TKDGIEALSSRPFRNVSRQTSRQMS LCGTPEKSSYRQLSVSDRSSIRVEE IIPAARVAIQTMEVSDFTST VACFMRLSWAAAAGRLDLVGSSQPI KESNSLCPAGIRNRLSSSGSNCSSG SEGEPVALHAGICVRQQSVS TKDSLIAGEALSLLVTCLQLRSQQL ASFYNLPCVADFIIDILLGSPSAEI RRVACDQLYTLSQTDTSAHP DVQKPNQFLLGVILTAQLPLWSPTS IMRGVNQRLLSQCMEYFDLRCQLLD DLTTSEMEQLRISPATMLED EITWLDNFEPNRTAECETSEADNIL LAGHLRLIKTLLSLCGAEKEMLGSS LIKPLLDDFLFRASRIILNS HSPAGSAAISQQDFHPKCSTANSRL AAYEVLVMLADSSPSNLQIIIKELL SMHHQPDPALTKEFDYLPPV DSRSSSGFVGLRNGGATCYMNAVFQ QLYMQPGLPESLLSVDDDTDNPDDS VFYQVQSLFGHLMESKLQYY VPENFWKIFKMWNKELYVREQQDAY EFFTSLIDQMDEYLKKMGRDQIFKN TFQGIYSDQKICKDCPHRYE REEAFMALNLGVTSCQSLEISLDQF VRGEVLEGSNAYYCEKCKEKRITVK RTCIKSLPSVLVIHLMRFGF DWESGRSIKYDEQIRFPWMLNMEPY TVSGMARQDSSSEVGENGRSVDQGG GGSPRKKVALTENYELVGVI VHSGQAHAGHYYSFIKDRRGCGKGK WYKFNDTVIEEFDLNDETLEYECFG GEYRPKVYDQTNPYTDVRRR YWNAYMLFYQRVSDQNSPVLPKKSR VSVVRQEAEDLSLSAPSSPEISPQS SPRPHRPNNDRLSILTKLVK KGEKKGLFVEKMPARIYQMVRDENL KFMKNRDVYSSDYFSFVLSLASLNA TKLKHPYYPCMAKVSLQLAI QFLFQTYLRTKKKLRVDTEEWIATI EALLSKSFDACQWLVEYFISSEGRE LIKIFLLECNVREVRVAVAT ILEKTLDSALFYQDKLKSLHQLLEV LLALLDKDVPENCKNCAQYFFLFNT FVQKQGIRAGDLLLRHSALR HMISFLLGASRQNNQIRRWSSAQAR EFGNLHNTVALLVLHSDVSSQRNVA PGIFKQRPPISIAPSSPLLP LHEEVEALLFMSEGKPYLLEVMFAL RELTGSLLALIEMVVYCCFCNEHFS FTMLHFIKNQLETAPPHELK NTFQLLHEILVIEDPIQVERVKFVF ETENGLLALMHHSNHVDSSRCYQCV KFLVTLAQKCPAAKEYFKEN SHHWSWAVQWLQKKMSEHYWTPQSN VSNETSTGKTFQRTISAQDTLAYAT ALLNEKEQSGSSNGSESSPA
  NENGDRHLQQGSESPMMIGELRSDL DDVDPTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Protease

Gene Information

• Gene Name: USP24 ubiquitin specific peptidase 24 [ Homo sapiens (human) ]
• Official Symbol: USP24
• Synonyms: FLJ31309; KIAA1057
• Gene ID: 23358
• mRNA Refseq: NM_015306.3
• Protein Refseq: NP_056121.2
• MIM: 610569
• UniProt ID: Q9UPU5