Active Recombinant Human BDNF Protein
| Cat.No. : | BDNF-143H |
| Product Overview : | Recombinant Human Brain-Derived Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding His129-Arg247 is expressed. |
- Specification
- Gene Information
- Related Products
| Description : | Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease. |
| Source : | E. coli |
| Species : | Human |
| Form : | Lyophilized from a 0.2 um filtered solution of 20mM PB, 250mM NaCl, pH 7.2. |
| Bio-activity : | Immobilized Human BDNF at 2ug/mll (100 μl/well) can bind Human TrkB-His. The ED50 of Human BDNF is 2-10 ug/ml. |
| Molecular Mass : | Predicted Molecular Weight: 13kDa Apparent Molecular Weight: 14kDa, reducing conditions. |
| AA Sequence : | His129-Arg247 |
| Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
| Purity : | >95% |
| Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. |
| Quality Statement : | Purity: Greater than 95% as determined by reducing SDS-PAGE. |
| Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
| Gene Name : | BDNF brain derived neurotrophic factor [ Homo sapiens (human) ] |
| Official Symbol : | BDNF |
| Synonyms : | Brain-Derived Neurotrophic Factor; Abrineurin; ANON2; BULN2 |
| Gene ID : | 627 |
| mRNA Refseq : | NM_001143805.1 |
| Protein Refseq : | NP_001137277.1 |
| MIM : | 113505 |
| UniProt ID : | P23560 |
Products Types
| ◆ Lysates | ||
| BDNF-001MCL | Recombinant Mouse BDNF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket
