Active Recombinant Human BRDT, His&FLAG-tagged
Cat.No. : | BRDT-37H |
Product Overview : | Recombinant Human BRDT corresponding to amino acids 21-137 that contains the bromodomain sequences of BRDT (accession number NP_001717.2) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag. |
- Specification
- Gene Information
- Related Products
Description : | BRDT is similar to the RING3 protein family. It possesses two bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain functions as a "reader" of epigenetic histone marks and regulates chromatin structure and gene expression by linking associated proteins to the recognized acetylated nucleosomal targets. |
Source : | E. coli |
Species : | Human |
Tag : | His&FLAG |
Form : | 25 mM HEPES pH 7.5, 150 mM NaCl and 5% glycerol. |
Bio-activity : | Binding specificity for acetylated H2BK12/15, H3K9/14/18/23, H4K12, H4K5/8, H4K8/12, H4K12/16, H4K5/12, H4K5/8/12/16 and H4K5/8/12/16. |
Molecular Mass : | 20 kDa |
Applications : | Binding assays, inhibitor screening, and selectivity profiling. |
Storage : | Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage. |
Concentration : | 1.9 mg/ml |
Gene Name : | BRDT bromodomain, testis-specific [ Homo sapiens ] |
Official Symbol : | BRDT |
Synonyms : | BRDT; bromodomain, testis-specific; bromodomain testis-specific protein; BRD6; cancer/testis antigen 9; CT9; RING3-like protein; |
Gene ID : | 676 |
mRNA Refseq : | NM_001242805 |
Protein Refseq : | NP_001229734 |
MIM : | 602144 |
UniProt ID : | Q58F21 |
Chromosome Location : | 1p22.1 |
Function : | histone binding; protein serine/threonine kinase activity; transcription coactivator activity; |
Products Types
◆ Recombinant Protein | ||
BRDT-1249H | Recombinant Human BRDT Protein (N21-E137), His/SUMO tagged | +Inquiry |
BRDT-1089M | Recombinant Mouse BRDT Protein, His (Fc)-Avi-tagged | +Inquiry |
BRDT-1248H | Recombinant Human BRDT Protein (N21-E137), Tag Free | +Inquiry |
BRDT-59H | Recombinant Human BRDT protein, GST-tagged | +Inquiry |
BRDT-1915H | Recombinant Human BRDT, His-tagged | +Inquiry |
◆ Assay kits | ||
Kit-1702 | BRDT (BD1+BD2) TR-FRET Assay Kit | +Inquiry |
Kit-1933 | BRDT bromodomain 1 TR-FRET Assay Kit | +Inquiry |
Kit-1643 | HEK 293 BRDT(1,2) Bromodomain Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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