Active Recombinant Human CCL4 Protein (Ala24-Asn92), Animal-free, Carrier-free
Cat.No. : | CCL4-269H |
Product Overview : | Recombinant Human CCL4 Protein (Ala24-Asn92) without tag was expressed in E. coli and Animal-free as well as Carrier-free. |
- Specification
- Gene Information
- Related Products
Description : | C-C Motif Chemokine Ligand 4 (CCL4) is a 7.66 kDa cytokine with 69 amino acid residues. CCL4, also named macrophage inflammatory protein-1β (MIP-1β), is mainly secreted from neutrophils, monocytes, B cells, T cells, fibroblasts, endothelial cells and epithelial cells. CCL4 recruits various immune cells like natural killer cells, monocytes, and neutrophils when CCL4 binds to CCR5. In addition, CCL4 mediates lymphocyte adhesion by Rac1 /Cdc42 signaling pathway and plays critical roles in different biological functions like maintenance of cell polarity, regulation of calcium ion transport and response to viruses. |
Source : | E. coli |
Species : | Human |
Tag : | Tag Free |
Form : | Lyophilized |
Bio-activity : | Measure by its ability to chemoattract BaF3 cells transfected with human CCR5. The ED50 for this effect is < 10 ng/mL. |
Molecular Mass : | The protein has a calculated MW of 7.75 kDa. The protein migrates as 11 kDa under reducing condition (SDS-PAGE analysis). |
Protein Length : | Ala24-Asn92 |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | >98% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution containing 50 mM Tris and 150 mM NaCl, pH 8.5. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name : | CCL4 chemokine (C-C motif) ligand 4 [ Homo sapiens (human) ] |
Official Symbol : | CCL4 |
Synonyms : | CCL4; chemokine (C-C motif) ligand 4; LAG1, SCYA4, small inducible cytokine A4 (homologous to mouse Mip 1b); C-C motif chemokine 4; Act 2; AT744.1; MIP 1 beta; PAT 744; SIS-gamma; MIP-1-beta(1-69); CC chemokine ligand 4; secreted protein G-26; T-cell activation protein 2; small-inducible cytokine A4; lymphocyte-activation gene 1; G-26 T-lymphocyte-secreted protein; lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; small inducible cytokine A4 (homologous to mouse Mip-1b); ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; MIP-1-beta; MGC104418; MGC126025; MGC126026; |
Gene ID : | 6351 |
mRNA Refseq : | NM_002984 |
Protein Refseq : | NP_002975 |
MIM : | 182284 |
UniProt ID : | P13236 |
Products Types
◆ Recombinant Protein | ||
CCL4-4390C | Recombinant Cynomolgus Monkey CCL4 Protein | +Inquiry |
CCL4-2149H | Recombinant Human CCL4 Protein, His-tagged | +Inquiry |
Ccl4-26M | Active Recombinant Mouse CCL4 Protein | +Inquiry |
CCL4-2936H | Recombinant Human CCL4 Protein | +Inquiry |
CCL4-023H | Recombinant Human CCL4 Protein, Biotinylated | +Inquiry |
◆ Lysates | ||
CCL4-7721HCL | Recombinant Human CCL4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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