Active Recombinant Human CD200 Chimera Protein

• Cat.No.: CD200-03H
• Product Overview: Recombinant Human CD200 Chimera Protein was expressed in mouse myeloma cell line

Specification

• Description: This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: Mouse myeloma cell line
• Species: Human
• Form: Lyophilized
• Bio-activity: Measured by its binding ability in a functional ELISA. When Recombinant Human CD200 R1 Chimera is immobilized at 2 μg/mL (100 μL/well), the concentration of Recombinant Human CD200 Fc Chimera that produces 50% of the optimal binding response is appoximately 2.5‑15 ng/mL.
• Molecular Mass: 49 kDa (monomer)
• N-terminal Sequence Analysis: No results obtained: Gln31 predicted
• Endotoxin: <0.10 EU per 1 ug of the protein by the LAL method.
• Purity: >90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 °C as supplied.
  1 month, 2 to 8 °C under sterile conditions after reconstitution.
  3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS.
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS.
• Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
• Structure / Form: Disulfide-linked homodimer

Gene Information

• Gene Name: CD200 CD200 molecule [ Homo sapiens (human) ]
• Official Symbol: CD200
• Synonyms: antigen identified by monoclonal MRC OX-2; CD200 antigenMOX1; CD200 molecule; CD200; MOX1; MOX2; MOX2MRC; MRC OX-2 antigen; MRC; OX-2 membrane glycoprotein; OX-2
• Gene ID: 4345
• mRNA Refseq: NM_001004196.4
• Protein Refseq: NP_001004196.2
• MIM: 155970
• UniProt ID: P41217