Active Recombinant Human CD276 Protein, Fc-tagged, Alexa Fluor 555 conjugated
Cat.No. : | CD276-542HAF555 |
Product Overview : | The Alexa Fluor 555 conjugated recombinant human B7-H3-Fc fusion is expressed as a 448 amino acid protein consisting of Leu29 - Ala248 region of B7-H3 (UniProt accession #Q5ZPR3 - isoform 2) and a C-terminal Fc fusion from human IgG1, which exists as a dimer under non-reducing condition. |
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- Gene Information
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Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Bio-activity : | Inhibits anti-CD3-induced proliferation of stimulated human T cells. Binds anti-B7-H3 monoclonal antibodies, human IgG1 and rabbit IgG in a functional ELISA. |
Molecular Mass : | Calculated molecular mass 49.2 kDa; estimated by SDS-PAGE under reducing condition 65-70 kDa probably due to glycosylation |
AA Sequence : | LEVQVPEDPVVALVGTDATLCCSFS PEPGFSLAQLNLIWQLTDTKQLVHS FAEGQDQGSAYANRTALFPDLLAQ GNASLRLQRVRVADEGSFTCFVSIR DFGSAAVSLQVAAPYSKPSMTLEPN KDLRPGDTVTITCSSYRGYPEAEV FWQDGQGVPLTGNVTTSQMANEQGL FDVHSVLRVVLGANGTYSCLVRNPV LQQDAHGSVTITGQPMTFPPEAST GTHTCPPCPAPELLGGPSVFLFPPK PKDTLMISRTPEVTCVVVDVSHEDP EVKFNWYVDGVEVHNAKTKPREEQ YNSTYRVVSVLTVLHQDWLNGKEYK CKVSNKALPAPIEKTISKAKGQPRE PQVYTLPPSREEMTKNQVSLTCLV KGFYPSDIAVEWESNGQPENNYKTT PPVLDSDGSFFLYSKLTVDKSRWQQ GNVFSCSVMHEALHNHYTQKSLSL SPGK |
Endotoxin : | < 0.1 EU/ μg of purified recombinant protein determined by the LAL method |
Purity : | > 95 % by SDS-PAGE under reducing condition |
Characteristic : | Disulfide-linked homodimer Labeled with Alexa Fluor 555 via amines With an excitation and emission maximum of 555/565 nm, Alexa Fluor 555 can be efficiently excited using a 543 nm He-Ne laser line and detected under standard TRITC/Cy3 filters. |
Storage : | The product is shipped at 4 centigrade. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20 centigrade for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4 centigrade for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Supplied at 0.5 mg/ml in sterile PBS pH 7.4 (carrier free). |
Gene Name : | CD276 CD276 molecule [ Homo sapiens ] |
Official Symbol : | CD276 |
Synonyms : | CD276; CD276 molecule; CD276 antigen; B7 H3; B7H3; B7RP 2; B7 homolog 3; costimulatory molecule; B7-H3; B7RP-2; 4Ig-B7-H3; |
Gene ID : | 80381 |
mRNA Refseq : | NM_001024736 |
Protein Refseq : | NP_001019907 |
MIM : | 605715 |
UniProt ID : | Q5ZPR3 |
Products Types
◆ Recombinant Protein | ||
CD276-502H | Recombinant Human CD276 Protein (ECD) (Met1-Thr461), HIgG1 Fc-tagged, Biotinylated | +Inquiry |
CD276-1238H | Recombinant Human CD276 protein(Met1-Thr243), His-tagged | +Inquiry |
CD276-1363H | Recombinant Human CD276 protein(Met1-Thr461), hFc-tagged, Biotinylated | +Inquiry |
Cd276-1140M | Recombinant Mouse Cd276 protein(Met1-Phe244), His-tagged, Biotinylated | +Inquiry |
CD276-599H | Recombinant Human CD276 Protein | +Inquiry |
◆ Lysates | ||
CD276-826RCL | Recombinant Rat CD276 cell lysate | +Inquiry |
CD276-001MCL | Recombinant Mouse CD276 cell lysate | +Inquiry |
CD276-1959HCL | Recombinant Human CD276 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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