Active Recombinant Human CD3D Protein (Phe22-Ala105), C-Fc-tagged
Cat.No. : | CD3D-28H |
Product Overview : | Recombinant human CD3 delta/CD3d protein (Phe22-Ala105) with a Human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in Human embryonic kidney cell. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. |
Source : | HEK293 |
Species : | Human |
Tag : | C-Fc |
Form : | Disulfide linked homodimer |
Bio-activity : | Measured by its binding ability in a functional ELISA. When Recombinant Human CD3 delta/CD3d Fc Chimera is immobilized at 1.0 μg/mL, 100 μL/well, the concentration of Recombinant Human CD3E Fc Chimera Biotinylated Protein that produces 50% of the optimal binding response is approximately 1.0-6.0 μg/mL. |
Molecular Mass : | Predicted Molecular Mass: 36 kDa SDS-PAGE: 45-55 kDa, under reducing conditions |
Protein Length : | Phe22-Ala105 |
Endotoxin : | <0.10 EU/μg of the protein by the LAL method. |
Purity : | >95% by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution : | Reconstitute at 250 μg/mL in PBS. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | CD3D CD3d molecule, delta (CD3-TCR complex) [ Homo sapiens (human) ] |
Official Symbol : | CD3D |
Synonyms : | CD3D; CD3d molecule, delta (CD3-TCR complex); CD3d antigen, delta polypeptide (TiT3 complex) , T3D; T-cell surface glycoprotein CD3 delta chain; CD3 delta; OKT3, delta chain; CD3 antigen, delta subunit; T-cell receptor T3 delta chain; CD3d antigen, delta polypeptide (TiT3 complex); T3D; CD3-DELTA |
Gene ID : | 915 |
mRNA Refseq : | NM_000732 |
Protein Refseq : | NP_000723 |
MIM : | 186790 |
UniProt ID : | P04234 |
Products Types
◆ Recombinant Protein | ||
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CD3D-673D | Recombinant Dog CD3D Protein, His-tagged | +Inquiry |
CD3D-0799H | Recombinant Human CD3D Protein | +Inquiry |
◆ Lysates | ||
CD3D-1274HCL | Recombinant Human CD3D cell lysate | +Inquiry |
CD3D-1381MCL | Recombinant Mouse CD3D cell lysate | +Inquiry |
CD3D-1466CCL | Recombinant Cynomolgus CD3D cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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