Active Recombinant Human CD46 protein, hFc-tagged

• Cat.No.: CD46-0381H
• Product Overview: Recombinant Human CD46 protein(P15529)(35-328aa), fused to C-terminal hFc tag, was expressed in Mammalian cell.

Specification

• Source: Mammalian cell
• Species: Human
• Tag: hFc
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Bio-activity: Measured by its binding ability in a functional ELISA. Immobilized CD46 at 2 μg/ml can bind Anti-CD46 rabbit monoclonal antibody, the EC50 of human CD46 protein is 0.8333-1.054 ng/ml.
• Molecular Mass: 61.6 kDa
• Protein length: 35-328aa
• AA Sequence: CEEPPTFEAMELIGKPKPYYEIGER VDYKCKKGYFYIPPLATHTICDRNH TWLPVSDDACYRETCPYIRDPLNGQ AVPANGTYEFGYQMHFICNEGYYLI GEEILYCELKGSVAIWSGKPPICEK VLCTPPPKIKNGKHTFSEVEVFEYL DAVTYSCDPAPGPDPFSLIGESTIY CGDNSVWSRAAPECKVVKCRFPVVE NGKQISGFGKKFYYKATVMFECDKG FYLDGSDTIVCDSNSTWDPPVPKCL KVLPPSSTKPPALSHSVSTSSTTKS PASSASGPRPTYKPPVSNY
• Endotoxin: Less than 1.0 EU/ug as determined by LAL method.
• Purity: Greater than 92% as determined by SDS-PAGE.
• Storage: Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Gene Information

• Gene Name: CD46 CD46 molecule, complement regulatory protein [ Homo sapiens ]
• Official Symbol: CD46
• Synonyms: CD46; CD46 molecule, complement regulatory protein; antigen identified by monoclonal TRA 2 10 , CD46 antigen, complement regulatory protein , MCP, membrane cofactor protein (CD46, trophoblast lymphocyte cross reactive antigen) , MIC10; membrane cofactor protein; MGC26544; TLX; TRA2.10; measles virus receptor; complement membrane cofactor protein; trophoblast leucocyte common antigen; trophoblast leukocyte common antigen; CD46 antigen, complement regulatory protein; trophoblast-lymphocyte cross-reactive antigen; antigen identified by monoclonal TRA-2-10; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); MCP; AHUS2; MIC10
• Gene ID: 4179
• mRNA Refseq: NM_002389
• Protein Refseq: NP_002380
• MIM: 120920
• UniProt ID: P15529