Active Recombinant Human CD80, HIgG1 Fc-tagged
Cat.No. : | CD80-617H |
Product Overview : | The extracellular domain of human CD80 [B7-1] (NP_005182.1) (Val35-Asn242) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO cell. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. Theactivated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor foradenovirus subgroup B and may play a role in lupus neuropathy |
Source : | CHO cells |
Species : | Human |
Tag : | HIgG1 Fc-tagged |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Bio-activity : | Measured by its ability to induce IL-2 secretion by Jurkat human acute T cell leukemia cells. |
Molecular Mass : | 50 KDa (monomer) |
AA Sequence : | Val35-Asn242 |
Endotoxin : | <0.06 eu/μg as determined by lal test.>0.06> |
Purity : | >98%, by SDS-PAGE under reducing conditions. |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Reconstitution : | Reconstitute at 100μg/ml in sterile PBS. |
Warning : | Avoid freeze/thaw cycles. |
Gene Name : | CD80 CD80 molecule [ Homo sapiens ] |
Official Symbol : | CD80 |
Synonyms : | CD80; CD80 molecule; CD28LG, CD28LG1, CD80 antigen (CD28 antigen ligand 1, B7 1 antigen) , CD80 molecule; T-lymphocyte activation antigen CD80; B lymphocyte activation antigen B7; B7 1; B7.1; activation B7-1 antigen; costimulatory factor CD80; CTLA-4 counter-receptor B7.1; B-lymphocyte activation antigen B7; costimulatory molecule variant IgV-CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); B7; BB1; B7-1; LAB7; CD28LG; CD28LG1; |
Gene ID : | 941 |
mRNA Refseq : | NM_005191 |
Protein Refseq : | NP_005182 |
MIM : | 112203 |
UniProt ID : | P33681 |
Chromosome Location : | 3q13.3-q21 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem; |
Function : | coreceptor activity; protein binding; receptor activity; |
Products Types
◆ Recombinant Protein | ||
CD80-591M | Recombinant Mouse CD80 Protein, Fc-tagged | +Inquiry |
CD80-38H | Recombinant Human CD80 Protein (ECD), His-tagged(C-ter) | +Inquiry |
CD80-1376H | Acitve Recombinant Human CD80 protein(Met1-Asn242), His&Avi-tagged, Biotinylated | +Inquiry |
CD80-0859H | Recombinant Human CD80 Protein | +Inquiry |
CD80-547H | Recombinant Human CD80 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CD80-2715HCL | Recombinant Human CD80 cell lysate | +Inquiry |
CD80-1767MCL | Recombinant Mouse CD80 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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