Active Recombinant Human CD81 Protein, Fc-tagged

• Cat.No.: CD81-01H
• Product Overview: Recombinant Human CD81 Protein, fused to Fc-tag, was expressed in CHO Cells.

Specification

• Description: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.
• Source: CHO Cells
• Species: Human
• Tag: Fc
• Form: Lyophilized from a 0.2 μm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA. When Recombinant Human CD81 LEL Fc Chimera is used at 2 μg/mL, Recombinant Viral HCV E2 binds with an ED50 of 0.2-1.2 µg/mL.
• Molecular Mass: Predicted Molecular Mass: 36 kDa
  SDS-PAGE: 36-41 kDa, reducing conditions
• N-terminal Sequence Analysis: Met
• Endotoxin: <0.10 EU per 1 μg of the protein by the LAL method.
• Purity: >95%
• Applications: Bioactivity
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Reconstitution: Reconstitute at 100 μg/mL in PBS.
• Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
• tmpcolum67: CD81 molecule

Gene Information

• Gene Name: CD81 CD81 molecule [ Homo sapiens (human) ]
• Official Symbol: CD81
• Synonyms: S5.7; CVID6; TAPA1; TSPAN28
• Gene ID: 975
• mRNA Refseq: NM_004356
• Protein Refseq: NP_004347
• MIM: 186845
• UniProt ID: P60033