Active Recombinant Human CTGF protein, Fc-tagged

• Cat.No.: CTGF-2607H
• Product Overview: Recombinant Human CTGF protein(Q5M8T4-1)(Gln27-Ala349), fused to N-terminal Fc tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: Fc
• Form: Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.
• Bio-activity: Immobilized Human CTGF, Fc Tag at 5 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CTGF Antibody, Human IgG1 with a linear range of 0.8-6 ng/mL.
• Molecular Mass: The protein has a calculated MW of 61.9 kDa. The protein migrates as 55-60 kDa and 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Protein Length: Gln27-Ala349
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >90% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 centigrade to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: CTGF connective tissue growth factor [ Homo sapiens ]
• Official Symbol: CTGF
• Synonyms: CTGF; connective tissue growth factor; CCN2; IGFBP8; IBP-8; IGFBP-8; CCN family member 2; IGF-binding protein 8; hypertrophic chondrocyte-specific protein 24; insulin-like growth factor-binding protein 8; NOV2; HCS24; MGC102839
• Gene ID: 1490
• mRNA Refseq: NM_001901
• Protein Refseq: NP_001892
• MIM: 121009
• UniProt ID: P29279

Reviews

03/22/2021

Its purity, stability, and consistency ensure reliable and reproducible results, giving me confidence in the integrity of my research findings.

08/06/2019

With their assistance, I can overcome obstacles and optimize my experimental setup.

09/23/2018

With the CTGF protein and the manufacturer's support, I am confident in obtaining accurate and meaningful results for my scientific investigations.

Q&As

How can CTGF be measured or detected in clinical settings?

CTGF levels can be measured using various techniques, including enzyme-linked immunosorbent assay (ELISA) and immunohistochemistry.

What are the potential diagnostic applications of CTGF in medicine?

CTGF levels can serve as diagnostic markers for fibrotic diseases, aiding in the early detection and monitoring of such conditions.

Are there therapeutic implications of targeting CTGF in clinical practice?

Yes, targeting CTGF is being explored as a potential therapeutic strategy to mitigate fibrosis in various organs and tissues.

In which medical specialties is CTGF protein research particularly relevant?

CTGF protein research is particularly relevant in specialties such as rheumatology, pulmonology, and dermatology due to its implications in fibrotic diseases.

How does CTGF contribute to fibrosis?

CTGF plays a crucial role in promoting the formation of fibrous tissue by stimulating the production of extracellular matrix proteins.