Active Recombinant Human CTLA4 Protein, His-Tagged
Cat.No. : | CTLA4-01H |
Product Overview : | Recombinant Human CTLA4 Protein, His-Tagged was expressed in Baculovirus cell |
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- Gene Information
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Description : | This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. |
Source : | Baculovirus |
Species : | Human |
Tag : | His |
Form : | Liquid |
Bio-activity : | The activity is determined by the IL-2 ELISA in a using Jurkat human acute T cell leukemia cells. The ED50 range ≤150ng/ml with Human B7 1/CD80. |
Molecular Mass : | 40.8 kDa (368aa) |
Endotoxin : | < 1 EU per 1ug of protein (determined by LAL method) |
Purity : | > 95% by SDS-PAGE |
Applications : | SDS-PAGE, Bioactivity |
Storage : | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5mg/ml (determined by absorbance at 280nm) |
Storage Buffer : | Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Name : | CTLA4 cytotoxic T-lymphocyte associated protein 4 [ Homo sapiens (human) ] |
Official Symbol : | CTLA4 |
Synonyms : | Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA4, ALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12, ATGP3364 |
Gene ID : | 1493 |
mRNA Refseq : | NM_001037631.3 |
Protein Refseq : | NP_001032720.1 |
MIM : | 123890 |
UniProt ID : | P16410 |
Products Types
◆ Recombinant Protein | ||
CTLA4-109C | Active Recombinant Cynomolgus/Rhesus CTLA4 protein(Met1-Asp161), His-tagged | +Inquiry |
CTLA4-902R | Recombinant Rhesus Macaque CTLA4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ctla4-651H | Recombinant Human Ctla4 Protein, IgG2a Fc-tagged | +Inquiry |
CTLA4-870H | Recombinant Human CTLA4 Protein, His&SUMO-tagged | +Inquiry |
CTLA4-024H | Recombinant Human CTLA4 Protein, C-His-tagged | +Inquiry |
◆ Lysates | ||
CTLA4-1047CCL | Recombinant Cynomolgus CTLA4 cell lysate | +Inquiry |
CTLA4-2179MCL | Recombinant Mouse CTLA4 cell lysate | +Inquiry |
CTLA4-2526HCL | Recombinant Human CTLA4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1713 | CTLA4[Biotinylated]:B7-2 Inhibitor Screening Assay Kit | +Inquiry |
Kit-1712 | CTLA4:B7-1[Biotinylated] Inhibitor Screening Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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