Active Recombinant Human DGKA protein, GST-tagged
Cat.No. : | DGKA-181H |
Product Overview : | Recombinant Human DGKA fused with GST tag at N-terminal was expressed in Insect cells. |
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Description : | Diacylglycerol kinase alpha (DAG kinase alpha) is a member of the eukaryotic diacylglycerol kinase family. Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resyn-thesis of phosphatidylinositols and attenuating protein kinase C activity. Involved in hepatocellular carcinoma progression through regulation of the Ras/Raf/MEK/ERK pathway. The DGKα/atypical PKC/β1 integrin signaling pathway is required for matrix invasion of breast carcinoma cells. |
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 3000 nmol/min/mg |
Molecular Mass : | 105 kDa |
Purity : | >90% |
Applications : | Kinase Assay |
Stability : | 1 year at -70 centigrade from the date of shipment. |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | DGKA diacylglycerol kinase, alpha 80kDa [ Homo sapiens ] |
Official Symbol : | DGKA |
Synonyms : | DGKA; diacylglycerol kinase, alpha 80kDa; DAGK, DAGK1, diacylglycerol kinase, alpha (80kD); diacylglycerol kinase alpha; DGK alpha; DAG kinase alpha; diglyceride kinase alpha; 80 kDa diacylglycerol kinase; DAGK; DAGK1; DGK-alpha; MGC12821; MGC42356; |
Gene ID : | 1606 |
mRNA Refseq : | NM_001345 |
Protein Refseq : | NP_001336 |
MIM : | 125855 |
UniProt ID : | P23743 |
Chromosome Location : | 12q13.3 |
Pathway : | Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Effects of PIP2 hydrolysis, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Glycerolipid metabolism, organism-specific biosystem; Glycerolipid metabolism, conserved biosystem; Glycerophospholipid metabolism, organism-specific biosystem; |
Function : | ATP binding; calcium ion binding; diacylglycerol kinase activity; nucleotide binding; phospholipid binding; transferase activity; |
Products Types
◆ Recombinant Protein | ||
DGKA-1512R | Recombinant Rat DGKA Protein, His (Fc)-Avi-tagged | +Inquiry |
DGKA-2096H | Recombinant Human DGKA Protein (1-735 aa), His-tagged | +Inquiry |
Dgka-677M | Recombinant Mouse Dgka Protein, His-tagged | +Inquiry |
DGKA-751H | Recombinant Human DGKA Protein, His (Fc)-Avi-tagged | +Inquiry |
Dgka-678R | Recombinant Rat Dgka Protein, His-tagged | +Inquiry |
◆ Lysates | ||
DGKA-6961HCL | Recombinant Human DGKA 293 Cell Lysate | +Inquiry |
DGKA-6960HCL | Recombinant Human DGKA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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