Active Recombinant Human FBN1 Protein, Fc-tagged
Cat.No. : | FBN1-02H |
Product Overview : | Recombinant Human Fibrillin-1 (Ala25-Thr660) with a Human IgG1 (Pro100-Lys330) Fc tag at C-terminus was expressed in Mouse myeloma cell line. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome. |
Source : | Mouse myeloma cell line |
Species : | Human |
Tag : | Fc |
Form : | Disulfide-linked homodimer |
Bio-activity : | Measured by its binding ability in a functional ELISA. When Recombinant Human MFAP4 is immobilized at 0.5 μg/mL (100 μL/well), the concentration of Recombinant Human Fibrillin-1/FBN1 Fc Chimera that produces 50% of the optimal binding response is 0.1-0.6 μg/mL. |
Molecular Mass : | 95kDa |
Endotoxin : | < 0.10 EU/μg of the protein by the LAL method. |
Purity : | > 95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
Reconstitution : | Reconstitute at 500 μg/mL in PBS. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | FBN1 fibrillin 1 [ Homo sapiens (human) ] |
Official Symbol : | FBN1 |
Synonyms : | FBN1; fibrillin 1; FBN; SGS; WMS; MASS; MFLS; MFS1; OCTD; SSKS; WMS2; ACMICD; ECTOL1; GPHYSD2; fibrillin-1; asprosin; epididymis secretory sperm binding protein; fibrillin 15; fibrillin-1 preproprotein |
Gene ID : | 2200 |
mRNA Refseq : | NM_000138 |
Protein Refseq : | NP_000129 |
MIM : | 134797 |
UniProt ID : | P35555 |
Products Types
◆ Recombinant Protein | ||
FBN1-01HCL | Recombinant Human FBN1 Over-expression Lysate, C-Myc/DDK tagged | +Inquiry |
FBN1-3878H | Recombinant Human FBN1 Protein, GST-tagged | +Inquiry |
FBN1-371H | Recombinant Human FBN1 Protein, His-tagged | +Inquiry |
FBN1-2737H | Recombinant Human FBN1 protein(2701-2870 aa), C-His-tagged | +Inquiry |
FBN1-01H | Active Recombinant Human FBN1 Protein, Fc-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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