Active Recombinant Human FUT8 Protein (AA 41-575), N-6×His/GFP tagged

• Cat.No.: FUT8-31H
• Product Overview: Recombinant Human FUT8 Protein (AA 41-575) with N-6×His/GFP tag was expressed in HEK293.

Specification

• Description: This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: N-6×His, GFP
• Bio-activity: ≥10.3 μmol/min/mg
• Molecular Mass: ~75-80 kDa
• Protein Length: AA 41-575
• AA Sequence: RELSKILAKLERLKQQNEDLRRMAE SLRIPEGPIDQGPAIGRVRVLEEQL VKAKEQIENKKQTRNGLGKDHEILR RRIENGAKELWFFLQSELKKLKNLE GNELQRHADEFLLDLGHHERSIMTD LYYLSQTDGAGDWREKEAKDLTELV QRRITYLQNPKDCSKAKKLVCNINK GCGYGCQLHHVVYCFMIAYGTQRTL ILESQNWRYATGGWETVFRPVSETC TDRSGISTGHWSGEVKDKNVQVVEL PIVDSLHPRPPYLPLAVPEDLADRL VRVHGDPAVWWVSQFVKYLIRPQPW LEKEIEEATKKLGFKHPVIGVHVRR TDKVGTEAAFHPIEEYMVHVEEHFQ LLARRMQVDKKRVYLATDDPSLLKE AKTKYPNYEFISDNSISWSAGLHNR YTENSLRGVILDIHFLSQADFLVCT FSSQVCRVAYEIMQTLHPDASANFH SLDDIYYFGGQNAHNQIAIYAHQPR TADEIPMEPGDIIGVAGNHWDGYSK GVNRKLGRTGLYPSYKVREKIETVK YPTYPEAEK
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by Coomassie Blue stain.
• Stability: 6 months if stored at -80 centigrade. Avoid repeated freeze thaws.
• Concentration: 1 mg/mL
• Storage Buffer: Supplied as a 0.2 μm filtered solution in 20mM HEPES pH 7.0 and 100mM NaCl buffer, with 10% Glycerol.
• Preservative: 0.05 % NaN3
• Shipping: This product is shipped as 0.2μm filtered product on dry ice.

Gene Information

• Gene Name: FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) [ Homo sapiens (human) ]
• Official Symbol: FUT8
• Synonyms: FUT8; fucosyltransferase 8 (alpha (1,6) fucosyltransferase); alpha-(1,6)-fucosyltransferase; alpha1-6FucT; glycoprotein 6-alpha-L-fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; MGC26465
• Gene ID: 2530
• mRNA Refseq: NM_178155
• Protein Refseq: NP_835368
• MIM: 602589
• UniProt ID: Q9BYC5