Active Recombinant Human HDAC1, GST-tagged
Cat.No. : | HDAC1-1353H |
Product Overview : | Full-length recombinant human HDAC1 was expressed by baculovirus in Sf9 insect cells using a C-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | HDAC1 or Histone deacetylase 1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex which plays a key role in the regulation of eukaryotic gene expression. HDAC1 interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effect on cell growth and apoptosis. HDAC1 is an essential element of the co-activation system for IFN-induced gene regulation and antiviral responses. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 8900 RLU/min/ng |
Molecular Mass : | ~88 kDa |
Protein length : | Full length |
Purity : | >70% |
Applications : | HDAC Assay, Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | HDAC1 histone deacetylase 1 [ Homo sapiens ] |
Official Symbol : | HDAC1 |
Synonyms : | HDAC1; histone deacetylase 1; RPD3L1; GON 10; HD1; reduced potassium dependency, yeast homolog-like 1; RPD3; GON-10; DKFZp686H12203; |
Gene ID : | 3065 |
mRNA Refseq : | NM_004964 |
Protein Refseq : | NP_004955 |
MIM : | 601241 |
UniProt ID : | Q13547 |
Chromosome Location : | 1p34 |
Pathway : | Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; |
Function : | NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); RNA polymerase II transcription corepressor activity; activating transcription factor binding; core promoter binding; enzyme binding; histone deacetylase activity; histone deacetylase activity; histone deacetylase activity; histone deacetylase activity (H3-K16 specific); histone deacetylase binding; hydrolase activity; protein binding; protein deacetylase activity; protein deacetylase activity; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription factor binding; |
Products Types
◆ Recombinant Protein | ||
Hdac1-3366M | Recombinant Mouse Hdac1 Protein, Myc/DDK-tagged | +Inquiry |
HDAC1-060H | Recombinant Human HDAC1 Protein, His/FLAG-tagged | +Inquiry |
HDAC1-2469R | Recombinant Rat HDAC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
HDAC1-20R | Recombinant Rat HDAC1 protein(Met1~Ala482), His-tagged | +Inquiry |
HDAC1-4638H | Recombinant Human HDAC1 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
HDAC1-5608HCL | Recombinant Human HDAC1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-2283 | HDAC1 Immunoprecipitation (IP) & Activity Assay Kit | +Inquiry |
Kit-1737 | HDAC1 Kinetic Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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