Active Recombinant Human INHBA Protein, Pre-aliquoted

• Cat.No.: INHBA-25H
• Product Overview: Recombinant Human INHBA Protein, Gly311-Ser426, was expressed in CHO.

Specification

• Description: This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients.
• Source: CHO
• Species: Human
• Bio-activity: Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50 for this effect is 0.2-1.2 ng/mL.
• Molecular Mass: Predicted Molecular Mass:13 kDa (monomer)
  SDS-PAGE: 14 kDa, reducing conditions, 24 kDa, non-reducing conditions
• Protein length: Gly311-Ser426
• N-terminal Sequence Analysis: Gly311
• Endotoxin: < 0.01 EU/μg of the protein by the LAL method.
• Purity: > 95% by SDS-PAGE under reducing conditions and visualized by silver stain.
• Stability: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 6 months from date of receipt at room temperature as supplied.
  • 12 months from date of receipt at 2-8 centigrade as supplied.
  • 1 month at 2-8 centigrade under sterile conditions after reconstitution.
  • 3 months at -20 to -80 centigrade under sterile conditions after reconstitution.
• Reconstitution: For a stock solution, reconstitute at 100 μg/mL in 4 mM HCl, or simply roll Pre-aliquoted directly into cell culture medium for immediate use.
• Shipping: The product is shipped at ambient temperature.

Gene Information

• Gene Name: INHBA inhibin subunit beta A [ Homo sapiens (human) ]
• Official Symbol: INHBA
• Synonyms: INHBA; inhibin subunit beta A; EDF; FRP; inhibin beta A chain; FSH-releasing protein; Inhibin, beta-1; activin beta-A chain; erythroid differentiation factor; erythroid differentiation protein; follicle-stimulating hormone-releasing protein; inhibin beta A subunit; inhibin, beta A (activin A, activin AB alpha polypeptide)
• Gene ID: 3624
• mRNA Refseq: NM_002192
• Protein Refseq: NP_002183
• MIM: 147290
• UniProt ID: P08476