Active Recombinant Human ITGA1 Protein, C-6×His-tagged
Cat.No. : | ITGA1-27H |
Product Overview : | Recombinant Human Integrin alpha 1 (Met1-Pro1141, Acidic Tail) with a 6×His tag at C-terminus and Human Integrin beta 1 (Gln21-Asp728, Basic Tail) was expressed in Chinese Hamster Ovary cell line. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. |
Source : | CHO |
Species : | Human |
Tag : | C-6×His |
Bio-activity : | Measured by its binding ability in a functional ELISA. When Collagen I is immobilized at 5 μg/mL, Recombinant Human Integrin alpha 1 beta 1 can bind with an apparent KD <5 nM. Optimal dilutions should be determined by each laboratory for each application. |
Molecular Mass : | Predicted Molecular Mass: 132.3 kDa (Integrin alpha 1) & 86.4 kDa (Integrin beta 1) SDS-PAGE: 180-200 & 110-130 kDa, reducing conditions |
Protein Length : | Integrin alpha 1: Met1-Pro1141 Integrin beta 1: Gln21-Asp728 |
N-terminal Sequence Analysis : | Phe29 (Integrin alpha 1) & No results obtained: Gln21 predicted (Integrin beta 1), sequencing might be blocked |
Endotoxin : | <1.0 EU/μg of the protein by the LAL method. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution : | Reconstitute at 100 μg/mL in PBS. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | ITGA1 integrin subunit alpha 1 [ Homo sapiens (human) ] |
Official Symbol : | ITGA1 |
Synonyms : | ITGA1; integrin subunit alpha 1; VLA1; CD49a; integrin alpha-1; CD49 antigen-like family member A; VLA-1; laminin and collagen receptor; very late activation protein 1; very late antigen-1 |
Gene ID : | 3672 |
mRNA Refseq : | NM_181501 |
Protein Refseq : | NP_852478 |
MIM : | 192968 |
UniProt ID : | P56199 |
Products Types
◆ Recombinant Protein | ||
ITGA1-5002H | Recombinant Human ITGA1 Protein, GST-tagged | +Inquiry |
ITGA1-2767R | Recombinant Rat ITGA1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ITGA1-6626C | Recombinant Chicken ITGA1 | +Inquiry |
ITGA1-6797H | Recombinant Human ITGA1 protein, His-tagged | +Inquiry |
Itga1-6799R | Recombinant Rat Itga1 protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
ITGA1-5137HCL | Recombinant Human ITGA1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket