Active Recombinant Human JAK3 Protein, His-tagged

• Cat.No.: JAK3-467H
• Product Overview: Recombinant human JAK3 (781-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag.

Specification

• Description: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
• Source: Insect cells
• Species: Human
• Tag: His
• Bio-activity: 252 nmol/min/mg
• Molecular Mass: 40kDa
• Purity: >80%
• Stability: One year at -70 centigrade from the date of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.2 μg/μL
• Storage Buffer: Recombinant protein stored in PBS.
• Shipping: Shipped on dry ice.

Gene Information

• Gene Name: JAK3 Janus kinase 3 [ Homo sapiens (human) ]
• Official Symbol: JAK3
• Synonyms: JAK3; Janus kinase 3; JAKL; LJAK; JAK-3; L-JAK; tyrosine-protein kinase JAK3; Janus kinase 3 (a protein tyrosine kinase, leukocyte); leukocyte Janus kinase; EC 2.7.10.2
• Gene ID: 3718
• mRNA Refseq: NM_000215
• Protein Refseq: NP_000206
• MIM: 600173
• UniProt ID: P52333