Active Recombinant Human KDM1A protein, GST-tagged
Cat.No. : | KDM1A-15H |
Product Overview : | Recombinant Human KDM1A(158–end) fused with GST tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a nuclear protein containing a SWIRM domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Form : | 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 16 mM glutathione |
Bio-activity : | ≥0.50 pmole/min/μg |
Molecular Mass : | 104 kDa |
Purity : | ≥67% |
Applications : | Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
Storage : | At least 6 months at –80 centigrade. Avoid freeze/thaw cycles. Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%). |
Concentration : | 3.0 mg/ml |
Gene Name : | KDM1A lysine (K)-specific demethylase 1A [ Homo sapiens ] |
Official Symbol : | KDM1A |
Synonyms : | KDM1A; lysine (K)-specific demethylase 1A; amine oxidase (flavin containing) domain 2 , AOF2, KDM1, lysine (K) specific demethylase 1; lysine-specific histone demethylase 1A; BHC110; KIAA0601; LSD1; lysine (K)-specific demethylase 1; BRAF35-HDAC complex protein BHC110; lysine-specific histone demethylase 1; amine oxidase (flavin containing) domain 2; FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit; flavin-containing amine oxidase domain-containing protein 2; AOF2; KDM1; |
Gene ID : | 23028 |
mRNA Refseq : | NM_015013 |
Protein Refseq : | NP_055828 |
MIM : | 609132 |
UniProt ID : | O60341 |
Chromosome Location : | 1p36.12 |
Pathway : | Coregulation of Androgen receptor activity, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hemostasis, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem; |
Function : | MRF binding; androgen receptor binding; chromatin binding; demethylase activity; enzyme binding; flavin adenine dinucleotide binding; histone demethylase activity; histone demethylase activity (H3-K4 specific); histone demethylase activity (H3-K9 specific); histone demethylase activity (H3-dimethyl-K4 specific); ligand-dependent nuclear receptor transcription coactivator activity |
Products Types
◆ Recombinant Protein | ||
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Kdm1a-3680M | Recombinant Mouse Kdm1a Protein, Myc/DDK-tagged | +Inquiry |
KDM1A-1240H | Recombinant Human KDM1A Protein, His (Fc)-Avi-tagged | +Inquiry |
KDM1A-350H | Recombinant Human KDM1A Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
KDM1A-001HCL | Recombinant Human KDM1A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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