Active Recombinant Human MSLN Protein, Fc-tagged, Alexa Fluor 488 conjugated
Cat.No. : | MSLN-185HAF488 |
Product Overview : | Alexa Fluor 488 conjugated recombinant human MSLN protein, fused to Fc-tag, was expressed in HEK293 Cells. |
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Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized |
Bio-activity : | Testing in progress |
Molecular Mass : | The recombinant human MSLN/Fc is a disulfide-linked homodimer. The reduced monomer comprises 545 amino acids and has a predicted molecular mass of 60.7 kDa. The apparent molecular mass of the protein is approximately 65 kDa in SDS-PAGE under reducing conditions due to glycosylation. |
Protein length : | 545 |
N-terminal Sequence Analysis : | Glu |
Endotoxin : | < 1.0 EU/ μg of the protein as determined by the LAL method. |
Purity : | > 85 % as determined by SDS-PAGE |
Characteristic : | Disulfide-linked homodimer Labeled with Alexa Fluor 488 via amines Excitation Wavelength: 488 nm Emission Wavelength: 515-545 nm |
Stability : | Samples are stable for up to 12 months from date of receipt at -70 centigrade. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. |
Gene Name : | MSLN |
Official Symbol : | MSLN |
Synonyms : | Mesothelin; MPF; SMRP; MSLN; mesothelin; CAK1 antigen; megakaryocyte potentiating factor; pre-pro-megakaryocyte-potentiating factor; soluble MPF mesothelin related protein |
Gene ID : | 10232 |
mRNA Refseq : | NM_005823 |
Protein Refseq : | NP_005814 |
MIM : | 601051 |
UniProt ID : | Q13421 |
Products Types
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MSLN-25C | Recombinant Cynomolgus MSLN Protein, Fc tagged | +Inquiry |
MSLN-072H | Recombinant Human MSLN Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
MSLN-3449R | Recombinant Rat MSLN Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
MSLN-1343HCL | Recombinant Human MSLN cell lysate | +Inquiry |
MSLN-1316HCL | Recombinant Human MSLN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMSLN is normally expressed in mesothelial cells, playing a role in cell adhesion.
In cancer, MSLN expression is significantly upregulated.
MSLN is overexpressed in mesothelioma, ovarian, and pancreatic cancers.
Therapies targeting MSLN include antibody-drug conjugates and CAR-T cell therapies.
MSLN levels can be assessed through immunohistochemistry and serum biomarker tests.
MSLN overexpression is often associated with poor prognosis in cancer patients.
MSLN promotes tumor cell proliferation, invasion, and resistance to apoptosis.
Customer Reviews (3)
Write a reviewVery satisfied, great product.
Product is high-quality.
Excellent for experiments, reliable.
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