Active Recombinant Human MSLN protein, Fc-tagged, Biotinylated
Cat.No. : | MSLN-0389H |
Product Overview : | Biotinylated Recombinant Human MSLN protein(Glu296-Gly580), fused with Fc tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant. |
Bio-activity : | Immobilized Anti-Human MSLN Mab at 0.5 μg/mL (100 μL/well) can bind Biotinylated Human Mesothelin (296-580) Protein, Fc Tag, primary amine labeling with a linear range of 0.5-8 ng/mL. |
Molecular Mass : | This protein carries a human IgG1 Fc tag at the N-terminusThe protein has a calculated MW of 59.1 kDa. The protein migrates as 60-68 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Proteinlength : | Glu296-Gly580 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. >90% as determined by SEC-MALS. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | MSLN mesothelin [ Homo sapiens ] |
Official Symbol : | MSLN |
Synonyms : | MSLN; mesothelin; CAK1; MPF; CAK1 antigen; megakaryocyte potentiating factor; soluble MPF mesothelin related protein; pre-pro-megakaryocyte-potentiating factor; SMRP; |
Gene ID : | 10232 |
mRNA Refseq : | NM_001177355 |
Protein Refseq : | NP_001170826 |
MIM : | 601051 |
UniProt ID : | Q13421 |
Products Types
◆ Recombinant Protein | ||
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MSLN-1339H | Recombinant Human MSLN protein(Met1-Arg286), hFc-tagged | +Inquiry |
MSLN-669M | Recombinant Mouse MSLN Protein (298-600 aa), His-SUMO-tagged | +Inquiry |
MSLN-384H | Recombinant Human MSLN Protein, His-tagged | +Inquiry |
MSLN-16H | Active Recombinant Human MSLN Protein, His-tagged, Alexa Fluor® 647 conjugated | +Inquiry |
◆ Lysates | ||
MSLN-1343HCL | Recombinant Human MSLN cell lysate | +Inquiry |
MSLN-1316HCL | Recombinant Human MSLN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMSLN is normally expressed in mesothelial cells, playing a role in cell adhesion.
In cancer, MSLN expression is significantly upregulated.
MSLN is overexpressed in mesothelioma, ovarian, and pancreatic cancers.
Therapies targeting MSLN include antibody-drug conjugates and CAR-T cell therapies.
MSLN levels can be assessed through immunohistochemistry and serum biomarker tests.
MSLN overexpression is often associated with poor prognosis in cancer patients.
MSLN promotes tumor cell proliferation, invasion, and resistance to apoptosis.
Customer Reviews (3)
Write a reviewVery satisfied, great product.
Product is high-quality.
Excellent for experiments, reliable.
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