Recombinant Human MUC16 protein(Asp12783-Ser13467), His-tagged
Cat.No. : | MUC16-10H |
Product Overview : | Recombinant Human MUC16 protein(Asp12783-Ser13467)(Q8WXI7) is expressed from HEK293 with His tag at the C-Terminus. |
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Source : | HEK293 |
Species : | Human |
Tag : | C-His |
Protein length : | Asp12783-Ser13467 |
Form : | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Bio-activity : | Immobilized Human CA125, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human MSLN, hFc Tag with the EC50 of 7.8ng/ml determined by ELISA. |
Molecular Mass : | The protein has a predicted MW of 76.17 kDa. Due to glycosylation, the protein migrates to 90-140 kDa based on Tris-Bis PAGE result. |
Endotoxin : | Less than 1EU per μg by the LAL method. |
Purity : | > 95% as determined by Tris-Bis PAGE > 95% as determined by HPLC |
Storage : | -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3-6 months after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Reconstitution : | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Gene Name : | MUC16 mucin 16, cell surface associated [ Homo sapiens ] |
Official Symbol : | MUC16 |
Synonyms : | MUC16; mucin 16, cell surface associated; mucin-16; CA125; FLJ14303; CA-125; MUC-16; CA125 ovarian cancer antigen; ovarian carcinoma antigen CA125; ovarian cancer-related tumor marker CA125 |
Gene ID : | 94025 |
mRNA Refseq : | NM_024690 |
Protein Refseq : | NP_078966 |
MIM : | 606154 |
UniProt ID : | Q8WXI7 |
Products Types
◆ Recombinant Protein | ||
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MUC16-28H | Recombinant Human MUC16 Protein, C-Fc-Avi tagged, Biotinylated | +Inquiry |
MUC16-0066H | Recombinant Human MUC16 Protein | +Inquiry |
MUC16-42H | Active Recombinant Human MUC16 Protein, His-tagged | +Inquiry |
MUC16-43H | Active Recombinant Human MUC16 Protein, Fc-Avi-tagged, Biotinylated | +Inquiry |
◆ Native Protein | ||
CDA002 | Active Native Human MUC16 Protein | +Inquiry |
MUC16-1H | Native Human MUC16 protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMUC16 works with other mucins and immune components to maintain epithelial barrier function and immune responses.
It aids in forming the mucosal barrier, protecting against pathogens and mechanical damage.
Targeting MUC16 in cancer therapy, especially in ovarian cancer, could be effective in inhibiting tumor growth and spread.
Altered MUC16 activity can impact the body's defense against inflammation and infection.
MUC16, a mucin protein, is essential for maintaining the protective mucous layer on epithelial surfaces.
MUC16 is associated with cancer progression, particularly in ovarian cancer, where it may facilitate tumor growth and metastasis.
Genetic variations in MUC16 can lead to differences in mucosal integrity and potentially influence cancer susceptibility.
Customer Reviews (3)
Write a reviewCritical for decision-making. Supports our research endeavors.
Expert service quality. Valuable for research integrity.
Dependable partner in experiments. Consistent and trustworthy.
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