Active Recombinant Human Neurexin 3
Cat.No. : | NRXN3-014H |
Product Overview : | A DNA sequence encoding the human NRXN3 isoform 2 (NP_620426.2) extracellular domain (Met 1-Thr 357) was fused with the Fc region of human IgG1 at the C-terminus. |
- Specification
- Gene Information
- Related Products
Cat. No. : | NRXN3-014H |
Description : | NRXN3 is a single-pass type I membrane protein which belongs to the neurexin family. It contains one laminin G-like domain. It is a neuronal cell surface protein that may be involved in cell recognition and cell adhesion. Neurexins are a family of proteins that function in the vertebrate nervous system as cell adhesion molecules and receptors. |
Source : | Human |
Host : | Human Cells |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
Purity : | > 95 % as determined by SDS-PAGE |
Bio-activity : | Measured by the ability of the immobilized protein to support the adhesion of C6 Rat brain glial cells. When 5x104 cells/well are added to NRXN3 coated plates (0.8 μg/mL and 100 μL/well), approximately 30%-50% will adhere specifically after 60 minutes at 37°C |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Stability : | Samples are stable for up to twelve months from date of receipt at -70°C. |
Predicted N terminal : | Ser 36 |
Molecular Mass : | The secreted recombinant human NRXN3/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 563 amino acids and predictes a molecular mass of 61.6 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh NRXN3/Fc monomer is approximately 75-85 kDa due to glycosylation. |
Storage : | Store it under sterile conditions at -70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | NRXN3 neurexin 3 [ Homo sapiens ] |
Official Symbol : | NRXN3 |
Synonyms : | NRXN3; neurexin 3; C14orf60; KIAA0743; MGC176711; neurexin-3-beta; neurexin III; neurexin III-beta; neurexin III-alpha |
Gene ID : | 9369 |
mRNA Refseq : | NM_138970 |
Protein Refseq : | NP_620426 |
MIM : | 600567 |
UniProt ID : | Q9HDB5 |
Chromosome Location : | 14q31 |
Pathway : | Cell adhesion molecules (CAMs) |
Function : | metal ion binding; receptor activity |
Products Types
◆ Recombinant Protein | ||
Nrxn3-1864M | Recombinant Mouse Nrxn3 Protein, His&GST-tagged | +Inquiry |
NRXN3-3749R | Recombinant Rat NRXN3 Protein, His (Fc)-Avi-tagged | +Inquiry |
NRXN3-2513H | Recombinant Human NRXN3 Protein, His-tagged | +Inquiry |
NRXN3-129H | Recombinant Human NRXN3 Protein, His (Fc)-Avi-tagged | +Inquiry |
NRXN3-6216M | Recombinant Mouse NRXN3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
NRXN3-1914HCL | Recombinant Human NRXN3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket