Active Recombinant Human Neuroligin 2, His-tagged
Cat.No. : | NLGN2-5692H |
Product Overview : | Recombinant Human NLGN2protein was expressed in Murine myeloma cell line with a C-terminal 6-Histag. Gln15-Ser660. |
- Specification
- Gene Information
- Related Products
Cat. No. : | NLGN2-5692H |
Description : | NLGN2 is one of severaltype I transmembrane Neuroligins that are expressed on neuronal postsynapticdensities. Neuroligins play an important role in synaptic development andfunction. Mature human NLGN2 is a 105 kDa protein that consists of a 663amino acid extracellular domain with a catalytically inactive cholinesterase-likedomain, a 21 aa transmembrane segment, and a 137 aa cytoplasmic tail. Withinthe ECD, human NLGN2 shares 98% aa sequence identity with mouse and ratNLGN2. |
Source : | Mammalian cells |
Form : | Lyophilized from a0.2 μm filtered solution in PBS. |
N-terminalSequence : | Gln15 predicted |
Molecular Weight : | 72 kDa |
Activity : | Measuredby its binding ability in a functional ELISA. When recombinant human NLGN2 is immobilized at 1.5 μg/mL, recombinant human Neurexin1β Fc Chimera binds with an apparent KD < 10 nM. |
Endotoxin Level : | <1.0 EUper 1 μg of the protein by the LAL method. |
SDS-PAGE : | 85-95kDa, reducing conditions. |
Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | 400μg/mL in PBS |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months fromdate of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterileconditions after reconstitution. 3 months, -20 to -70°C under sterile conditionsafter reconstitution. |
Gene Name : | NLGN2 neuroligin 2 [ Homosapiens ] |
Official Symbol : | NLGN2 |
Synonyms : | NLGN2; neuroligin 2;KIAA1366; neuroligin-2; OTTHUMP00000135277; EC 3.1.1; EC 3.1.1.1 |
Gene ID : | 57555 |
mRNA Refseq : | NM_020795 |
Protein Refseq : | NP_065846 |
MIM : | 606479 |
UniProt ID : | Q8NFZ4 |
Chromosome Location : | 17p13.2 |
Pathway : | Cell adhesion molecules (CAMs) |
Function : | NOT carboxylesterase activity; cell adhesionmolecule binding; neurexin family protein binding; receptor activity |
Products Types
◆ Recombinant Protein | ||
NLGN2-3635H | Recombinant Human NLGN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NLGN2-6089M | Recombinant Mouse NLGN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NLGN2-1832H | Recombinant Human NLGN2 Protein, His&GST-tagged | +Inquiry |
NLGN2-3655R | Recombinant Rat NLGN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
NLGN2-2861R | Recombinant Rhesus Macaque NLGN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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