Active Recombinant Human PDCD1 Protein, hIgG-tagged
Cat.No. : | PDCD1-06H |
Product Overview : | Recombinant human PD-1 (21-170aa), fused to hIgG-tag at C-terminus, was expressed in HEK293 cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. |
Source : | HEK293 |
Species : | Human |
Tag : | hIgG |
Form : | Liquid |
Bio-activity : | Measured by its binding ability in a functional ELISA with Human PD-L1/B7-H1. |
Molecular Mass : | 42.9 kDa (383aa) |
Protein length : | 21-170aa |
AA Sequence : | PGWFLDSPDRPWNPPTFSPALLVVT EGDNATFTCSFSNTSESFVLNWYRM SPSNQTDKLAAFPEDRSQPGQDCRF RVTQLPNGRDFHMSVVRARRNDSGT YLCGAISLAPKAQIKESLRAELRVT ERRAEVPTAHPSPSPRPAGQFQTLV |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | > 95% by SDS-PAGE |
Applications : | SDS-PAGE, Bioactivity |
Storage : | Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5 mg/mL (determined by absorbance at 280nm) |
Storage Buffer : | Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Gene Name : | PDCD1 programmed cell death 1 [ Homo sapiens (human) ] |
Official Symbol : | PDCD1 |
Synonyms : | PDCD1; programmed cell death 1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; programmed cell death 1 protein; protein PD-1; systemic lupus erythematosus susceptibility 2 |
Gene ID : | 5133 |
mRNA Refseq : | NM_005018 |
Protein Refseq : | NP_005009 |
MIM : | 600244 |
UniProt ID : | Q15116 |
Products Types
◆ Recombinant Protein | ||
PDCD1-2564H | Recombinant Human PDCD1 Protein, His-tagged | +Inquiry |
PDCD1-21H | Active Recombinant Human PDCD1 Protein, Fc-tagged, Alexa Fluor® 488 conjugated | +Inquiry |
PDCD1-698M | Recombinant Mouse PDCD1 Protein | +Inquiry |
PDCD1-1003C | Active Recombinant Cynomolgus PDCD1 protein(Met1-Gln167), hFc&Avi-tagged, Biotinylated | +Inquiry |
PDCD1-699M | Recombinant Mouse PDCD1 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
PDCD1-2628MCL | Recombinant Mouse PDCD1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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