Active Recombinant Human PDGFC Protein

• Cat.No.: PDGFC-096H
• Product Overview: The mature recombinant human PDGF-CC monomer protein containing 111aa (Val235-Gly345) without tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene.
• Source: E. coli
• Species: Human
• Bio-activity: Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is 70-350 ng/mL.
• Molecular Mass: 13.4 kDa
• Product-Related Proteins: 235-345
• Endotoxin: < 0.1 EU/μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: PDGFC platelet derived growth factor C [ Homo sapiens (human) ]
• Official Symbol: PDGFC
• Synonyms: PDGFC; platelet derived growth factor C; SCDGF; FALLOTEIN; platelet-derived growth factor C; Names; PDGF-C; VEGF-E; secretory growth factor-like protein; spinal cord-derived growth factor
• Gene ID: 56034
• mRNA Refseq: NM_016205
• Protein Refseq: NP_057289
• MIM: 608452
• UniProt ID: Q9NRA1