Active Recombinant Human PGAM2 protein, His-tagged (Bioactivity Validated)
Cat.No. : | PGAM2-15H |
Product Overview : | Recombinant human PGAM2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
- Specification
- Gene Information
- Related Products
Description : | PGAM2, also known as phosphoglycerate mutase 2, belongs to the phosphoglycerate mutase family. Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase efficiency, also known as glycogen storage disease X. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT |
Bio-activity : | Specific activity is >100units/mg, in which One unit will convert 1.0 umole of 3-phosphoglycerate to 2-phosphoglcerate per minute at pH 7.6 at 37centigrade. |
Molecular Mass : | 30.9 kDa (273aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MATHRLVMVR HGESTWNQEN RFCGWFDAEL SEKGTEEAKR GAKAIKDAKM EFDICYTSVL KRAIRTLWAI LDGTDQMWLP VVRTWRLNER HYGGLTGLNK AETAAKHGEE QVKIWRRSFD IPPPPMDEKH PYYNSISKER RYAGLKPGEL PTCESLKDTI ARALPFWNEE IVPQIKAGKR VLIAAHGNSL RGIVKHLEGM SDQAIMELNL PTGIPIVYEL NKELKPTKPM QFLGDEETVR KAMEAVAAQG KAK |
Purity : | > 95% by SDS - PAGE |
Storage : | Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | PGAM2 phosphoglycerate mutase 2 (muscle) [ Homo sapiens ] |
Official Symbol : | PGAM2 |
Synonyms : | PGAM2; phosphoglycerate mutase 2; PGAM M; BPG-dependent PGAM 2; GSD10; PGAMM; PGAM-M |
Gene ID : | 5224 |
mRNA Refseq : | NM_000290 |
Protein Refseq : | NP_000281 |
MIM : | 612931 |
UniProt ID : | P15259 |
Chromosome Location : | 7p13-p12 |
Pathway : | Gluconeogenesis, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, organism-specific biosystem; Gluconeogenesis, oxaloacetate => fructose-6P, conserved biosystem; Glucose metabolism, organism-specific biosystem; Glycine, serine and threonine metabolism, organism-specific biosystem; |
Function : | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity; bisphosphoglycerate 2-phosphatase activity; bisphosphoglycerate mutase activity; cofactor binding; hydrolase activity; isomerase activity; phosphoglycerate mutase activity; |
Products Types
◆ Recombinant Protein | ||
PGAM2-6658M | Recombinant Mouse PGAM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Pgam2-4816M | Recombinant Mouse Pgam2 Protein, Myc/DDK-tagged | +Inquiry |
PGAM2-4060R | Recombinant Rat PGAM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PGAM2-1657H | Recombinant Human PGAM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PGAM2-12674M | Recombinant Mouse PGAM2 Protein | +Inquiry |
◆ Lysates | ||
PGAM2-3263HCL | Recombinant Human PGAM2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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