Active Recombinant Human PIK3C3 protein, GST-tagged
Cat.No. : | PIK3C3-166H |
Product Overview : | Recombinant Human PIK3C3 fused with an N-terminal GST tag was expressed in Insect cells. |
- Specification
- Gene Information
- Related Products
Description : | PIK3C3 or phosphoinositide-3-kinase is a member of the PI 3-kinase family that mediates the active diversion of proteins from the secretory pathway to vacuoles. PIK3C3 are involved in both receptor-mediated signal transduction and intracellular trafficking. In yeast, the vps34 gene product is a PI 3-kinase. PIK3C3 has a substrate specificity and ion requirements that are distinct from the other known mammalian PI 3-kinases. PIK3C3 mediate catalysis on membranes and suppress futile adenosine triphosphatase cycles. PIK3C3 appears to alternate between a closed cytosolic form and an open form on the membrane. |
Source : | Insect cells |
Species : | Human |
Tag : | GST |
Form : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | 450 nmol/min/mg |
Molecular Mass : | 128 kDa |
Purity : | >85% |
Applications : | Kinase Assay |
Stability : | 1 year at -70 centigrade from the date of shipment |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1μg/μl |
Gene Name : | PIK3C3 phosphoinositide-3-kinase, class 3 [ Homo sapiens ] |
Official Symbol : | PIK3C3 |
Synonyms : | PIK3C3; phosphoinositide-3-kinase, class 3; phosphatidylinositol 3-kinase catalytic subunit type 3; Vps34; PI3K type 3; PI3-kinase type 3; PtdIns-3-kinase type 3; phosphatidylinositol 3-kinase p100 subunit; VPS34; hVps34; MGC61518; |
Gene ID : | 5289 |
mRNA Refseq : | NM_002647 |
Protein Refseq : | NP_002638 |
MIM : | 602609 |
UniProt ID : | Q8NEB9 |
Chromosome Location : | 18q12.3 |
Pathway : | 3-phosphoinositide biosynthesis, organism-specific biosystem; 3-phosphoinositide biosynthesis, conserved biosystem; IRS-mediated signalling, organism-specific biosystem; IRS-related events, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Inositol phosphate metabolism, organism-specific biosystem; |
Function : | 1-phosphatidylinositol-3-kinase activity; ATP binding; nucleotide binding; protein binding; protein kinase activity; |
Products Types
◆ Recombinant Protein | ||
PIK3C3-0213H | Recombinant Human PIK3C3 Protein (G2-K887), His/GST tagged | +Inquiry |
Pik3c3-4863M | Recombinant Mouse Pik3c3 Protein, Myc/DDK-tagged | +Inquiry |
PIK3C3-1678H | Recombinant Human PIK3C3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PIK3C3-4120R | Recombinant Rat PIK3C3 Protein, His (Fc)-Avi-tagged | +Inquiry |
PIK3C3-0212H | Recombinant Human PIK3C3 Protein (G2-K887), Tag Free | +Inquiry |
◆ Lysates | ||
PIK3C3-3190HCL | Recombinant Human PIK3C3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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