Active Recombinant Human RBP4 protein, His-tagged

• Cat.No.: RBP4-836H
• Product Overview: Recombinant Human RBP4 protein(NP_006735.2)(Met1-Leu201), fused with His tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized from sterile PBS, pH 7.2Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Bio-activity: Measured by its ability to bind all-trans retinoic acid. The binding of retinoic acid results in the quenching of Trp fluorescence in RBP4.The 50% binding concentration (BC50) is > 1.0 µM.
• Molecular Mass: The recombinant human RBP4 consists of 194 amino acids after removal of the signal peptide and migrates as an approximately 23 kDa protein as predicted.
• Protein Length: Met1-Leu201
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 85 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: RBP4 retinol binding protein 4, plasma [ Homo sapiens ]
• Official Symbol: RBP4
• Synonyms: RBP4; retinol binding protein 4, plasma; retinol-binding protein 4; RBP; PRBP; plasma retinol-binding protein; retinol-binding protein 4, interstitial
• Gene ID: 5950
• mRNA Refseq: NM_006744
• Protein Refseq: NP_006735
• UniProt ID: P02753

Reviews

06/17/2022

The manufacturer's dedicated and knowledgeable support team is readily available to address any concerns, provide guidance, and offer timely solutions.

01/16/2022

In addition to its impeccable quality, the manufacturer of the RBP4 protein provides outstanding technical support that can efficiently resolve any challenges encountered during my experiments.

12/09/2019

Such attentive support significantly minimizes potential setbacks and facilitates a seamless and efficient experimental process.

Q&As

Can RBP4 levels help predict the risk of developing certain cancers?

Studies have indicated a link between elevated RBP4 levels and a decreased risk of certain cancers, although more research is needed in this area.

Does RBP4 play a role in neurodegenerative diseases?

Some studies suggest a potential association between RBP4 levels and neurodegenerative disorders like Alzheimer's disease.

How is RBP4 involved in pregnancy?

RBP4 has been investigated in gestational diabetes, showing potential as a marker for metabolic complications during pregnancy.

Is RBP4 considered a reliable biomarker in clinical practice?

While RBP4 shows promise as a biomarker, its clinical utility is still under investigation and requires further validation.

Are there gender-specific differences in RBP4 levels?

Yes, research has shown that RBP4 levels can differ between genders, potentially affecting metabolic health differently.