Active Recombinant Human SFRP1, Fc-tagged, Biotinylated
Cat.No. : | SFRP1-672H |
Product Overview : | The recombinant human sFRP1-Fc is expressed as a 511-amino acid active form consisting of Ser32 - Lys314 region of sFRP1 (UniProt accession #Q8N474) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions. |
- Specification
- Gene Information
- Related Products
Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). The purified recombinant protein was labeled with Biotin (3-5 Biotin per molecule). |
Bio-activity : | Inhibits the proliferation of HeLa human cervical epithelial carcinoma cells with an ED50 of 0.2 - 0.8 μg/mL |
Molecular Mass : | Calculated molecular mass (kDa): 58.1; Estimated by SDS-PAGE under reducing condition (kDa): 75-85 |
AA Sequence : | SEYDYVSFQSDIGPYQSGRFYTKPP QCVDIPADLRLCHNVGYKKMVLPNL LEHETMAEVKQQASSWVPLLNKNC HAGTQVFLCSLFAPVCLDRPIYPCR WLCEAVRDSCEPVMQFFGFYWPEML KCDKFPEGDVCIAMTPPNATEASK PQGTTVCPPCDNELKSEAIIEHLCA SEFALRMKIKEVKKENGDKKIVPKK KKPLKLGPIKKKDLKKLVLYLKNG ADCPCHQLDNLSHHFLIMGRKVKSQ YLLTAIHKWDKKNKEFKNFMKKMKN HECPTFQSVFKSTGTHTCPPCPAP ELLGGPSVFLFPPKPKDTLMISRTP EVTCVVVDVSHEDPEVKFNWYVDGV EVHNAKTKPREEQYNSTYRVVSVL TVLHQDWLNGKEYKCKVSNKALPAP IEKTISKAKGQPREPQVYTLPPSRE EMTKNQVSLTCLVKGFYPSDIAVE WESNGQPENNYKTTPPVLDSDGSFF LYSKLTVDKSRWQQGNVFSCSVMHE ALHNHYTQKSLSLSPGK |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the lal>0.1> |
Purity : | >90% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | SFRP1 secreted frizzled-related protein 1 [ Homo sapiens ] |
Official Symbol : | SFRP1 |
Synonyms : | SFRP1; secreted frizzled-related protein 1; FRP; FRP 1; SARP2; SARP-2; sFRP-1; secreted apoptosis-related protein 2; FRP1; FrzA; FRP-1; |
Gene ID : | 6422 |
mRNA Refseq : | NM_003012 |
Protein Refseq : | NP_003003 |
MIM : | 604156 |
UniProt ID : | Q8N474 |
Chromosome Location : | 8p11.21 |
Pathway : | Validated targets of C-MYC transcriptional repression, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem; Wnt signaling pathway, organism-specific biosystem; Wnt signaling pathway, conserved biosystem; |
Function : | PDZ domain binding; Wnt-activated receptor activity; Wnt-protein binding; cysteine-type endopeptidase activity; drug binding; frizzled binding; heparin binding; identical protein binding; |
Products Types
◆ Recombinant Protein | ||
SFRP1-790M | Recombinant Mouse SFRP1 Protein (Met1-Lys314), His-tagged | +Inquiry |
SFRP1-364H | Recombinant Human SFRP1 Protein, His-tagged | +Inquiry |
SFRP1-3990R | Recombinant Rhesus Macaque SFRP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Sfrp1-366R | Recombinant Rat Sfrp1 Protein, His-tagged | +Inquiry |
SFRP1-4049H | Recombinant Human SFRP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SFRP1-2852MCL | Recombinant Mouse SFRP1 cell lysate | +Inquiry |
SFRP1-2853HCL | Recombinant Human SFRP1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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