Active Recombinant Human TDO2, MYC/DDK-tagged
Cat.No. : | TDO2-824H |
Product Overview : | Recombinant Human TDO2, fused with C-terminal MYC/DDK, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. |
Source : | HEK293 cells |
Species : | Human |
Tag : | MYC/DDK |
Bio-activity : | The specific activity of TDO2 was determined by monitoring Kynurenine formation from the N-formylkynurenine based on the absorbance at 492nm. |
Molecular Mass : | 47.7 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | TDO2 tryptophan 2,3-dioxygenase [ Homo sapiens (human) ] |
Official Symbol : | TDO2 |
Synonyms : | TDO; TPH2; TRPO; TDO2; tryptophan 2,3-dioxygenase; TO; tryptophanase; tryptophan oxygenase; tryptophan pyrrolase; tryptamin 2,3-dioxygenase; EC 1.13.11.11 |
Gene ID : | 6999 |
mRNA Refseq : | NM_005651 |
Protein Refseq : | NP_005642 |
MIM : | 191070 |
UniProt ID : | P48775 |
Chromosome Location : | 4q31-q32 |
Pathway : | Metabolic pathways; Tryptophan metabolism; Metabolism of amino acids and derivatives |
Function : | amino acid binding; heme binding; metal ion binding; oxidoreductase activity; oxygen binding; oxygen binding; tryptopha 2,3-dioxygenase activity |
Products Types
◆ Recombinant Protein | ||
TDO2-1536M | Recombinant Mouse TDO2 Protein (1-406 aa), His-tagged | +Inquiry |
TDO2-1535H | Recombinant Human TDO2 Protein (1-406 aa), His-tagged | +Inquiry |
TDO2-9103M | Recombinant Mouse TDO2 Protein, His (Fc)-Avi-tagged | +Inquiry |
TDO2-4170H | Recombinant Human TDO2 Protein, His (Fc)-Avi-tagged | +Inquiry |
TDO2-5656R | Recombinant Rat TDO2 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TDO2-1156HCL | Recombinant Human TDO2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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