Active Recombinant Human TGFB1 Protein
Cat.No. : | TGFB1-157H |
Product Overview : | Recombinant Human Transforming Growth Factor beta 1 is produced by our Mammalian expression system and the target gene encoding Ala279-Ser390 is expressed. |
- Specification
- Gene Information
- Related Products
Description : | Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease. |
Source : | CHO Cells |
Species : | Human |
Form : | Lyophilized from a 0.2 um filtered solution of 50mM Glycine 50mM NaCl pH4.0. |
Bio-activity : | Measured by its ability to inhibit the IL-4-dependent proliferation of TF‑1 human erythroleukemic cells. The ED50 for this effect is 4-40 pg/ml. |
AA Sequence : | Ala279-Ser390 |
Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
Purity : | >95% |
Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. |
Reconstitution : | It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Quality Statement : | Purity: >95% as determined by reducing SDS-PAGE |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Gene Name : | TGFB1 transforming growth factor beta 1 [ Homo sapiens (human) ] |
Official Symbol : | TGFB1 |
Synonyms : | TGF-beta-1; CED; DPD1; TGFB; TGF-b1; TGFB1; CEDLAP; latency-associated peptide; TGFbeta; TGF-beta 1 protein; transforming growth factor beta-1; LAP; IBDIMDE; TGFbeta; TGF-beta1 |
Gene ID : | 7040 |
mRNA Refseq : | NM_000660.7 |
Protein Refseq : | NP_000651.3 |
MIM : | 190180 |
UniProt ID : | P04202 |
Products Types
◆ Recombinant Protein | ||
TGFB1-299H | Recombinant Active Human TGFB1 Protein, His-tagged(C-ter) | +Inquiry |
TGFB1-1250H | Recombinant Human TGFB1 Protein, His-tagged | +Inquiry |
TGFB-13H | Recombinant Human TGFB1 Protein, Fc-tagged | +Inquiry |
TGFB1-363H | Active Recombinant Human TGFB1 Protein, His & Avi-tagged, Biotinylated | +Inquiry |
TGFB1-37H | Recombinant Human/Bovine/Porcine TGFB1 Protein | +Inquiry |
◆ Native Protein | ||
TGFB1-21H | Active Native Human TGF- β1 | +Inquiry |
◆ Lysates | ||
TGFB1-001MCL | Recombinant Mouse TGFB1 cell lysate | +Inquiry |
TGFB1-803RCL | Recombinant Rat TGFB1 cell lysate | +Inquiry |
TGFB1-001HCL | Recombinant Human TGFB1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket