Active Recombinant Human TIGIT protein, His-tagged
Cat.No. : | TIGIT-2347H |
Product Overview : | Recombinant Human TIGIT protein(NP_776160.2)(Met1-Phe138), fused with His tag, was expressed in HEK293. |
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Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | 1. Immobilized Human TIGIT His at 2 μg/mL (100 μL/well) can bind Human CD155/PVR hFc, the EC50 is 12-120 ng/mL. 2. Using the Octet RED System, the affinity constant (Kd) of TIGIT Protein, Human, Recombinant (His Tag) bound to MITG7192A was 0.1 nM. |
Molecular Mass : | The secreted recombinant human TIGIT comprises 128 amino acids with a predicted molecular mass of 14.2 kDa. As a result of glycosylation, human TIGIT migrates as an approximately 20.8 kDa band in SDS-PAGE under reducing conditions. |
Protein Length : | Met1-Phe138 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 90 % as determined by SDS-PAGE |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | TIGIT T cell immunoreceptor with Ig and ITIM domains [ Homo sapiens ] |
Official Symbol : | TIGIT |
Synonyms : | TIGIT; T cell immunoreceptor with Ig and ITIM domains; V set and immunoglobulin domain containing 9 , V set and transmembrane domain containing 3 , VSIG9, VSTM3; T-cell immunoreceptor with Ig and ITIM domains; DKFZp667A205; FLJ39873; V-set and transmembrane domain containing 3; V-set and immunoglobulin domain containing 9; Washington University cell adhesion molecule; V-set and transmembrane domain-containing protein 3; V-set and immunoglobulin domain-containing protein 9; VSIG9; VSTM3; WUCAM; |
Gene ID : | 201633 |
mRNA Refseq : | NM_173799 |
Protein Refseq : | NP_776160 |
MIM : | 612859 |
UniProt ID : | Q495A1 |
Products Types
◆ Recombinant Protein | ||
TIGIT-729H | Recombinant Human TIGIT Protein, IgG2a Fc-tagged | +Inquiry |
TIGIT-727H | Recombinant Human TIGIT Protein | +Inquiry |
TIGIT-1037H | Recombinant Human TIGIT Protein, MYC/DDK-tagged | +Inquiry |
TIGIT-728H | Recombinant Human TIGIT Protein, Fc-tagged | +Inquiry |
TIGIT-306H | Recombinant Human TIGIT Protein (ECD), His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
TIGIT-2610HCL | Recombinant Human TIGIT cell lysate | +Inquiry |
TIGIT-1420MCL | Recombinant Mouse TIGIT cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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