Active Recombinant Human TNF protein
Cat.No. : | TNF-242H |
Product Overview : | Recombinant Human TNF was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.0. |
Bio-activity : | ED50 is less than 0.03 ng/ml as determined by the cytolysis of murine L929 cells in the presence of Actinomycin D. Specific Activity of 3.0 x 10^7 IU/mg. |
Molecular Mass : | 17.5 kDa |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Storage : | Stable for at least 6 months from date of receipt under proper storage and handling conditions. |
Concentration : | Resuspend the protein to the desired concentration in proper buffer. |
Gene Name : | TNF tumor necrosis factor [ Homo sapiens ] |
Official Symbol : | TNF |
Synonyms : | TNF; tumor necrosis factor; TNFA, tumor necrosis factor (TNF superfamily, member 2); DIF; TNF superfamily; member 2; TNF alpha; TNFSF2; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived; TNF, macrophage-derived; TNF superfamily, member 2; tumor necrosis factor alpha; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2; TNFA; TNF-alpha; |
Gene ID : | 7124 |
mRNA Refseq : | NM_000594 |
Protein Refseq : | NP_000585 |
MIM : | 191160 |
UniProt ID : | P01375 |
Products Types
◆ Recombinant Protein | ||
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TNF-532H | Recombinant Human TNF Protein, His-tagged | +Inquiry |
TNF-4674R | Recombinant Rhesus Macaque TNF Protein, His (Fc)-Avi-tagged | +Inquiry |
TNF-529H | Recombinant Human TNF Protein, Biotinylated | +Inquiry |
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◆ Lysates | ||
TNF-897HCL | Recombinant Human TNF 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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