Active Recombinant Human TNFSF11 Protein (Glu143-Asp317), C-His tagged, Animal-free, Carrier-free
Cat.No. : | TNFSF11-302H |
Product Overview : | Recombinant Human TNFSF11 Protein (Glu143-Asp317) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free. |
- Specification
- Gene Information
- Related Products
Description : | Receptor activator of NF-κB (RANK) ligand (RANKL) is type II transmembrane protein with an extracellular domain at the carboxy-terminus of TNF cytokine superfamily. RANKL is a 19.8 kDa protein containing 317 residues and high express in T cells and T cell rich organs, such as thymus and lymph nodes. RANKL-RANK (RANKL receptor) plays an important role in bone metabolism, dysregulation, and immune system |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Form : | Lyophilized |
Bio-activity : | Measure by its ability to induce osteoclast differentiation in RAW264.7 cells. The ED50 for this effect is < 10 ng/mL. |
Molecular Mass : | The protein has a calculated MW of 20.67 kDa. The protein migrates as 17 kDa under reducing condition (SDS-PAGE analysis). |
Protein Length : | Glu143-Asp317 |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | >98% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name : | TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 [ Homo sapiens (human) ] |
Official Symbol : | TNFSF11 |
Synonyms : | TNFSF11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand superfamily member 11; CD254; ODF; OPGL; RANKL; TRANCE; osteoprotegerin ligand; osteoclast differentiation factor; TNF-related activation-induced cytokine; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; sOdf; OPTB2; hRANKL2; |
Gene ID : | 8600 |
mRNA Refseq : | NM_003701 |
Protein Refseq : | NP_003692 |
MIM : | 602642 |
UniProt ID : | O14788 |
Products Types
◆ Recombinant Protein | ||
TNFSF11-5859R | Recombinant Rat TNFSF11 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFSF11-2023M | Recombinant Mouse TNFSF11 Protein, His-tagged | +Inquiry |
TNFSF11-2025R | Recombinant Rat TNFSF11 Protein | +Inquiry |
TNFSF11-459H | Recombinant Human TNFSF11 Protein, His-tagged | +Inquiry |
TNFSF11-4498H | Recombinant Human TNFSF11 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TNFSF11-1586MCL | Recombinant Mouse TNFSF11 cell lysate | +Inquiry |
TNFSF11-1093HCL | Recombinant Human TNFSF11 cell lysate | +Inquiry |
TNFSF11-001CCL | Recombinant Cynomolgus TNFSF11 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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