Active Recombinant Human TNFSF12 Protein (Lys56-His249), C-His tagged, Animal-free, Carrier-free
Cat.No. : | TNFSF12-305H |
Product Overview : | Recombinant Human TNFSF12 Protein (Lys56-His249) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free. |
- Specification
- Gene Information
- Related Products
Description : | TNF-related weak inducer of apoptosis (TWEAK) is a type II membrane protein of the tumor necrosis factor (TNF) family members, high levels expression in human brain, muscle, heart, spleen, and thymus. TWEAK is a 17.3 kDa protein containing 129 residues. TWEAK induce apoptosis through cognate receptor Fn14 activate caspase-8 and caspase-3, in HSC3 cells KATO-III gastric adenocarcinoma cells and IFN-γ-treated HT-29. TWEAK stimulate inflammatory cytokines in HT-29, A375 cells, WI-38 fibroblast sand astrocytes. |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Form : | Lyophilized |
Bio-activity : | Measure by its ability to induce proliferation in HUVEC cells. The ED50 for this effect is < 6 ng/mL. |
Molecular Mass : | The protein has a calculated MW of 17.88 kDa. The protein migrates as 18 kDa under reducing condition (SDS-PAGE analysis). |
Protein Length : | Lys56-His249 |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | >98% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 8.0. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name : | TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 [ Homo sapiens (human) ] |
Official Symbol : | TNFSF12 |
Synonyms : | TNFSF12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand superfamily member 12; APO3L; DR3LG; TWEAK; APO3 ligand; APO3/DR3 ligand; TNF-related WEAK inducer of apoptosis; MGC20669; MGC129581; |
Gene ID : | 8742 |
mRNA Refseq : | NM_003809 |
Protein Refseq : | NP_003800 |
MIM : | 602695 |
UniProt ID : | O43508 |
Products Types
◆ Recombinant Protein | ||
Tnfsf12-86M | Active Recombinant Mouse Tnfsf12 Protein (His110-His249), C-His tagged, Animal-free, Carrier-free | +Inquiry |
TNFSF12-200T | Active Recombinant Human TNFSF12 Protein | +Inquiry |
TNFSF12-9483M | Recombinant Mouse TNFSF12 Protein, His (Fc)-Avi-tagged | +Inquiry |
TNFSF12-810M | Recombinant Mouse TNFSF12 Protein (Arg105-His249), RlgG Fc-tagged | +Inquiry |
TNFSF12-4686R | Recombinant Rhesus Macaque TNFSF12 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TNFSF12-1204RCL | Recombinant Rat TNFSF12 cell lysate | +Inquiry |
TNFSF12-1155CCL | Recombinant Cynomolgus TNFSF12 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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