Active Recombinant Human ULK1 Protein, 1-314, N-6×His tagged
Cat.No. : | ULK1-13H |
Product Overview : | Recombinant human ULK1 (amino acids 1-314) with N-terminal 6×His-tag was expressed by baculovirus in Sf21 insect cells, purified using immobilized metal affinity chromatography followed by gel filtration. |
- Specification
- Gene Information
- Related Products
Description : | Enables identical protein binding activity; protein serine/threonine kinase activity; and small GTPase binding activity. Involved in several processes, including autophagosome assembly; positive regulation by symbiont of host autophagy; and protein phosphorylation. Located in autophagosome; cytosol; and phagophore assembly site membrane. Is extrinsic component of autophagosome membrane; extrinsic component of omegasome membrane; and extrinsic component of phagophore assembly site membrane. Part of Atg1/ULK1 kinase complex. |
Source : | Insect cells |
Species : | Human |
Tag : | N-6×His |
Protein length : | 1-314 |
Form : | Frozen solution |
Bio-activity : | 2858 U/mg, where one unit of ULK1 activity is defined as 1 nmol phosphate incorporated into 2 mg/mL casein per minute at 30 centigrade with a final ATP concentration of 100 μM. |
Molecular Mass : | 39 kDa |
AA Sequence : | MSYYHHHHHHDYDIPTTENLYFQGA MDPEFMEPGRGGTETVGKFEFSRKD LIGHGAFAVVFKGRHREKHDLEVAV KCINKKNLAKSQTLLGKEIKILKEL KHENIVALYDFQEMANSVYLVMEYC NGGDLADYLHAMRTLSEDTIRLFLQ QIAGAMRLLHSKGIIHRDLKPQNIL LSNPAGRRANPNSIRVKIADFGFAR YLQSNMMAATLCGSPMYMAPEVIMS QHYDGKADLWSIGTIVYQCLTGKAP FQASSPQDLRLFYEKNKTLVPTIPR ETSAPLRQLLLALLQRNHKDRMDFD EFFHHPFLDASPSVRKSPPVPVPSY PSSGSGSSSSSSSTSHLAS |
Purity : | 83% by SDS-PAGE and Coomassie blue staining |
Applications : | Drug Discovery and Development |
Storage : | On receipt of material store at -70 centigrade. Unopened reagent is stable for a minimum of 1 year from date of shipment when stored at recommended storage temperature. Avoid repeat freeze/thaw cycles. For maximum recovery of product, centrifuge original vial prior to removing the cap. |
Concentration : | 0.45 mg/mL |
Storage Buffer : | 50 mM Tris/HCl pH 7.5, 300 mM NaCl, 0.1 mM EGTA, 0.03% Brij-35, 270 mM sucrose, 1 mM benzamidine, 0.2 mM PMSF, 0.1% 2-mercaptoethanol. |
Gene Name : | ULK1 unc-51 like autophagy activating kinase 1 [ Homo sapiens (human) ] |
Official Symbol : | ULK1 |
Synonyms : | ULK1; unc-51 like autophagy activating kinase 1; ATG1; ATG1A; UNC51; hATG1; Unc51.1; serine/threonine-protein kinase ULK1; ATG1 autophagy related 1 homolog; autophagy-related protein 1 homolog; EC 2.7.11.1 |
Gene ID : | 8408 |
mRNA Refseq : | NM_003565 |
Protein Refseq : | NP_003556 |
MIM : | 603168 |
UniProt ID : | O75385 |
Products Types
◆ Recombinant Protein | ||
ULK1-9903M | Recombinant Mouse ULK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ulk1-6830M | Recombinant Mouse Ulk1 Protein, Myc/DDK-tagged | +Inquiry |
ULK1-10H | Active Recombinant Human ULK1 protein, GST&Strep II-Tagged | +Inquiry |
ULK1-557H | Recombinant Human ULK1 Protein, MYC/DDK-tagged | +Inquiry |
ULK1-2313H | Recombinant Human ULK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ULK1-505HCL | Recombinant Human ULK1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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