Active Recombinant Human VEGFC Protein

• Cat.No.: VEGFC-108H
• Product Overview: The mature recombinant human VEGF-B protein (103-227aa) without tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors.
• Source: E. coli
• Species: Human
• Bio-activity: Measured in a cell proliferation assay using HMVEC human microvascular endothelial cells. The ED50 for this effect is 1-5 μg/mL. Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human VEGF R3/Flt-4 Fc Chimera at 5 μg/mL (100 μL/well) can bind Recombinant Human VEGF-C with an apparent Kd <40 nM.
• Molecular Mass: 15.4 kDa
• Product-Related Proteins: 103-227
• Storage: At -80 centigrade. Avoid repeated freeze-thaw cycles.
• Storage Buffer: PBS

Gene Information

• Gene Name: VEGFC vascular endothelial growth factor C [ Homo sapiens (human) ]
• Official Symbol: VEGFC
• Synonyms: VEGFC; vascular endothelial growth factor C; VRP; Flt4-L; LMPH1D; LMPHM4; vascular endothelial growth factor C; Names; FLT4 ligand DHM; vascular endothelial growth factor-related protein
• Gene ID: 7424
• mRNA Refseq: NM_005429
• Protein Refseq: NP_005420
• MIM: 601528
• UniProt ID: Q6FH59