Active Recombinant Mouse Alkaline Phosphatase, Liver/Bone/Kidney, His-tagged
Cat.No. : | Alpl-444M |
Product Overview : | Recombinant Mouse Alplprotein was expressed in Murine myeloma cell line. Phe18-Gly503, witha C terminal 6 His tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Alpl-444M |
Description : | Severaldistinct genes encode alkaline phosphatases (APs) in mice with differenttissuespecific expression patterns. The Alpl gene, also known as Akp2,encodes the liver/bone/kidney isozyme, also known as the tissuenonspecific AP(TNAP). The Alpl gene is a key regulator of bone mineralization in mice. Avariety of mutations in the human Alpl gene leads todifferent forms of hypophosphatasia, characterized by poorly mineralizedcartilage and bones. |
Source : | Mammalian cells |
Form : | Suppliedas a 0.2 um filtered solution in Tris and NaCl. |
N-terminalSequence : | Phe18 |
MolecularWeight : | 54 kDa |
Activity : | Measuredby its ability to cleave a fluorogenic substrate, 4Methylumbelliferyl phosphate(4MUP). The specific activity is > 40000 pmoles/min/μg, as measured underthe described conditions. See Activity Assay Protocol. |
Endotoxin Level : | <1.0EU per 1 μg of the protein by the LAL method. |
Purity : | >95%,by SDSPAGE under reducing conditions and visualized by silver stain. |
Storage : | Do notfreeze. 3months from date of receipt, 2 to 8°C as supplied. 1 month, 2 to 8°C understerile conditions after opening. |
Gene Name : | Alpl alkaline phosphatase,liver/bone/kidney [ Mus musculus ] |
Official Symbol : | Alpl |
Synonyms : | Alpl; alkalinephosphatase, liver/bone/kidney; Akp2; TNAP; Akp-2; APTNAP; TNSALP; alkalinephosphatase, tissue-nonspecific isozyme; alkaline phosphatase 2, liver; EC 3.1.3.1 |
Gene ID : | 11647 |
mRNA Refseq : | NM_007431 |
Protein Refseq : | NP_031457 |
UniProt ID : | P09242 |
Chromosome Location : | 4 |
Pathway : | Endochondral Ossification;Folate biosynthesis; Metabolic pathways; TNF-alpha NF-kB Signaling Pathway |
Function : | alkaline phosphataseactivity; catalytic activity; hydrolase activity; metal ion binding; phosphataseactivity |
Products Types
◆ Recombinant Protein | ||
ALPL-138R | Recombinant Rhesus Macaque ALPL Protein, His (Fc)-Avi-tagged | +Inquiry |
ALPL-001H | Recombinant Human ALPL Protein, His-tagged | +Inquiry |
ALPL-2155R | Recombinant Rat ALPL Protein (18-501 aa), His-SUMO-tagged | +Inquiry |
ALPL-2458H | Recombinant Human ALPL Protein, His (Fc)-Avi-tagged | +Inquiry |
ALPL-028H | Recombinant Human ALPL Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
◆ Native Protein | ||
ALPL-5324H | Active Native Human Alkaline Phosphatase | +Inquiry |
ALPL-8004H | Native Human Liver Alkaline Phosphatase | +Inquiry |
ALPL-66C | Active Native Calf Alkaline Phosphatase | +Inquiry |
◆ Lysates | ||
ALPL-3092HCL | Recombinant Human ALPL cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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