Active Recombinant Mouse Arylsulfatase G, His-tagged

• Cat.No.: Arsg-574M
• Product Overview: Recombinant Mouse Arsgprotein was expressed in Chinese Hamster Ovary cell line with a C-terminal 10-Histag. Gly17-Val525.

Specification

• Cat. No.: Arsg-574M
• Description: Arsg is a member ofthe aryl sulfatase family of enzymes with a high degree of amino acidsequence similarity to ARSA and ARSB. Arsg mRNA is expressed in a ubiquitousmanner, being detected in most adult and embryonic tissues of the mouse.
• Source: Chinese Hamster Ovarycell line, CHO-derived.
• Form: Supplied as a 0.2 μmfiltered solution in Tris and NaCl.
• N-terminalSequence: Gly17
• Molecular Weight: 57 kDa
• Activity: Measured by itsability to hydrolyze the substrate 4Nitrocatechol Sulfate (PNCS). Thespecific activity is > 1,500 pmoles/min/μg, as measured under thedescribed conditions.
• Endotoxin Level: < 1.0EU per 1 μg of the protein by the LAL method.
• SDS-PAGE: 65 kDa,reducing conditions.
• Purity: > 95%,by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Use a manual defrostfreezer and avoid repeated freezethaw cycles. 6 months from date of receipt, -20to -70°C as supplied. 3 months, -20 to -70°C under sterile conditions afteropening.

Gene Information

• Gene Name: Arsg arylsulfatase G [ Musmusculus ]
• Official Symbol: Arsg
• Synonyms: Arsg; arylsulfataseG; AI846872;6330406P08Rik; arylsulfatase G; ASG
• Gene ID: 74008
• mRNA Refseq: NM_001166177
• Protein Refseq: NP_001159649
• Chromosome Location: 11 E1; 11
• Pathway: Lysosome
• Function: arylsulfataseactivity; catalytic activity; hydrolase activity; metal ion binding; sulfuricester hydrolase activity

Reviews

07/26/2017

Its superior purity and stability ensure reliable and reproducible results, providing me with confidence in the integrity of my experiments.

06/20/2017

Whether I am investigating protein-protein interactions, studying enzymatic activity, or conducting protein structure analyses, the ARSG protein consistently delivers exceptional performance and accurate results.

02/03/2016

The ARSG protein is an exceptional product that meets the highest standards of quality, making it an ideal choice to fulfill my experimental requirements.

Q&As

Are there any diseases associated with mutations in the ARSG gene?

Currently, there are no known diseases directly associated with mutations in the ARSG gene. Further research is needed to determine if any mutations in this gene can cause specific health conditions.

Can ARSG be used as a therapeutic target?

Currently, there are no therapeutic strategies directly targeting ARSG due to limited knowledge of its function and disease associations. However, further research on its role in sulfated molecule metabolism may identify potential therapeutic applications in the future.

Is there any evidence linking ARSG to cancer?

There is limited scientific evidence linking ARSG to cancer. However, some studies have indicated its altered expression in certain cancer types, suggesting a potential association. Further research is necessary to understand the significance of ARSG in cancer development and progression.

Are there any known interacting proteins or pathways associated with ARSG?

The specific interacting proteins or pathways associated with ARSG are currently not well-established. Further research is required to understand its potential interactions and pathways in cellular processes.

Are there any known genetic variations in the ARSG gene?

Yes, genetic variations or single nucleotide polymorphisms (SNPs) have been identified in the ARSG gene. These variations may have implications for protein function, but their exact significance and impact on health are not yet fully understood.

Is there any ongoing research in relation to the ARSG protein?

While research on the ARSG protein is limited, ongoing studies aim to elucidate its biological function, substrate specificity, and potential roles in various cellular processes. Additionally, investigations may focus on understanding the consequences of ARSG mutations and exploring therapeutic strategies for related diseases, if any are identified in the future.