Active Recombinant Mouse Delta/Notch-Like EGF-Related Receptor
Cat.No. : | Dner-410M |
Product Overview : | Recombinantmouse Dner protein was expressed in Murine myeloma cell line, NS0-derived. Ala26-His637. |
- Specification
- Gene Information
- Related Products
- Download
Cat. No. : | Dner-410M |
Description : | Dner is a type Itransmembrane glycoprotein of the Notch/Delta family. Mouse Dner has beendetected as 90, 120 and 150 kDa forms which are probably variablyglycosylated. |
Source : | Mammalian cells |
Form : | Lyophilized from a0.2 μm filtered solution in PBS. |
N-terminal Sequence : | Ala26 |
Molecular Weight : | 91.4 kDa |
Activity : | Measured by itsability to inhibit Pleiotrophininduced neurite outgrowth of E16-E18 rat embryoniccortical neurons. When 4 x 104 neurons/well are added to 96well platecontaining serial dilutions of Recombinant Mouse DNER Fc Chimera andimmobilized Recombinant Mouse Pleiotrophin/PTN (1 μg/mL) neurite outgrowth issignificantly inhibited in a dose dependent manner. The ED50 forthis effect is typically 0.5-2.5 μg/mL. |
Endotoxin Level : | <1.0 EU per 1 μgof the protein by the LAL method. |
Purity : | >90%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
Reconstitution : | Reconstitute at 200μg/mL in PBS. |
Storage : | Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month,2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions afterreconstitution. |
Gene Name : | Dner delta/notch-likeEGF-related receptor [ Mus musculus ] |
Official Symbol : | Dner |
Synonyms : | Dner; delta/notch-likeEGF-related receptor; BET; Bret; A930026D19Rik; MGC39095; delta andNotch-like epidermal growth factor-related receptor; transmembrane proteinBet; brain EGF repeat-containing transmembrane protein; Bet |
Gene ID : | 227325 |
mRNA Refseq : | NM_152915 |
Protein Refseq : | NP_690879 |
UniProt ID : | Q8JZM4 |
Chromosome Location : | 1 |
Function : | receptor activity; calcium ion binding;Notch binding |
Products Types
◆ Recombinant Protein | ||
DNER-49H | Recombinant Human DNER Protein, His (Fc)-Avi-tagged | +Inquiry |
DNER-2784H | Recombinant Human DNER Protein, GST-tagged | +Inquiry |
Dner-25M | Recombinant Mouse Dner Protein, His (Fc)-Avi-tagged | +Inquiry |
Dner-838M | Active Recombinant Mouse Dner Protein, Fc Chimera | +Inquiry |
DNER-835H | Recombinant Human DNER | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All Dner Products
Required fields are marked with *
My Review for All Dner Products
Required fields are marked with *
0
Inquiry Basket