Active Recombinant Mouse Gas6, His-tagged

• Cat.No.: Gas6-483M
• Product Overview: Recombinant Mouse Gas6 (Accession # CAA42507) Ala46-Pro673, fused with a C-terminal 6-His tag, was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Mouse
• Tag: His
• Predicted N Terminal: Ala46 & Tyr47
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to down regulate the expression of Axl in DU145 human prostate carcinoma cells. Mishra, A. et al. (2012) Mol. Cancer Res. 10:703.The ED50 for this effect is typically 20-100 ng/mL.
• Molecular Mass: Recombinant Mouse Gas6, His-tagged has a calculated MW of 71 kDa. In SDS-PAGE migrates as 78-94 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE with silver staining.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: Gas6 growth arrest specific 6 [ Mus musculus ]
• Official Symbol: Gas6
• Synonyms: GAS6; growth arrest specific 6; growth arrest-specific protein 6; GAS 6; AXL receptor tyrosine kinase ligand; Gas-6
• Gene ID: 14456
• mRNA Refseq: NM_019521
• Protein Refseq: NP_062394