Active Recombinant Mouse Ifng
Cat.No. : | Ifng-11M |
Product Overview : | Recombinant murine IFN-γ is a 15.6 kDa protein containing 134 amino acid residues. |
- Specification
- Gene Information
- Related Products
Description : | IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. |
Source : | E.coli |
Species : | Mouse |
Bio-activity : | Determined by its ability to inhibit the proliferation of murine WEHI-279 cells. The expected ED50 is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 10^6 units/mg. |
Molecular Mass : | 15.6 kDa |
AA Sequence : | MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC |
Purity : | Greater than 98% by SDS-PAGE gel and HPLC analyses. |
Gene Name : | Ifng interferon gamma [ Mus musculus (house mouse) ] |
Official Symbol : | Ifng |
Synonyms : | Ifng; Ifg; IFN-g; interferon gamma; IFN-gamma; gamma interferon |
Gene ID : | 15978 |
mRNA Refseq : | NM_008337 |
Protein Refseq : | NP_032363 |
UniProt ID : | P01580 |
Chromosome Location : | 10 D2; 10 66.75 cM |
Pathway : | African trypanosomiasis; Allograft rejection; Antigen processing and presentation |
Function : | cytokine activity; interferon-gamma receptor binding |
Products Types
◆ Recombinant Protein | ||
IFNG-105I | Active Recombinant Human IFNG Protein (144 aa) | +Inquiry |
IFNG-116M | Active Recombinant Mouse IFNG Protein | +Inquiry |
IFNG-22H | Active Recombinant Human IFNG Protein | +Inquiry |
Ifng-078M | Active Recombinant Mouse Ifng Protein | +Inquiry |
Ifng-009I | Active Recombinant Rat Ifng Protein (135 aa) | +Inquiry |
◆ Lysates | ||
IFNG-001HCL | Recombinant Human IFNG cell lysate | +Inquiry |
IFNG-1007FCL | Recombinant Ferret IFNG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket