Active Recombinant Mouse LIGHT Protein, His-Tagged
Cat.No. : | LIGHT-01M |
Product Overview : | Recombinant mouse LIGHT Protein, His-tagged was expressed in E. coli cell |
- Specification
- Gene Information
- Related Products
Description : | LIGHT is a member of the TNF family of ligands, and can conduct signaling through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or binding to a decoy receptor, DcR3. LIGHT generally expresses in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT can also activate NF-κB, to co-stimulate the activation of lymphocytes and induce apoptosis in certain human tumor cells. |
Source : | Escherichia coli |
Species : | Mouse |
Tag : | His |
Form : | Lyophilized powder |
AA Sequence : | MRLHQRLGDIVAHLPDGGKGSWEKL IQDQRSHQANPAAHLTGANASLIGI GGPLLWETRLGLAFLRGLTYHDGAL VTMEPGYYYVYSKVQL SGVGCPQGLANGLPITHGLYKRTSR YPKELELLVSRRSPCGRANSSRVWW DSSFLGGVVHLEAGEEVVVRVPGNR LVRPRDGTRSYFGAFM V with polyhistidine tag at the C-terminus |
Endotoxin : | <0.1 EU per 1 μg of the protein by the LAL method. |
Bio-activity : | Measure by its ability to induce cytotoxicity in HT-29 cells. The ED50 for this effect is <2 μg/mL. |
Purity : | >98% as determined by SDS-PAGE. Ni-NTA chromatography |
Storage Buffer : | The protein was lyophilized from a solution containing 1X PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Storage : | Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C. |
Notes : | Please use within one month after protein reconstitution. |
Gene Name : | Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 [ Mus musculus (house mouse) ] |
Official Symbol : | LIGHT |
Synonyms : | LTg; HVEML; Tnfsf14; Ly113; HVEM-L; Tnlg1d |
Gene ID : | 50930 |
mRNA Refseq : | NM_019418.3 |
Protein Refseq : | NP_062291.1 |
UniProt ID : | Q059Y9 |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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