Active Recombinant Mouse Ptx3 Protein, His-tagged

• Cat.No.: Ptx3-01M
• Product Overview: Recombinant Mouse Ptx3 Protein Glu18-Ser381, with a C-terminal 6-His tag was expressed in Mouse myeloma cell line.

Specification

• Description: Enables (1->3)-beta-D-glucan binding activity. Acts upstream of or within several processes, including opsonization; ovarian cumulus expansion; and positive regulation of nitric oxide biosynthetic process. Located in extracellular matrix. Is expressed in cochlea; cochlea epithelium; inner ear vestibular component; organ of Corti; and stria vascularis. Human ortholog(s) of this gene implicated in cystic fibrosis and invasive aspergillosis. Orthologous to human PTX3 (pentraxin 3).
• Source: Mouse myeloma cell line
• Species: Mouse
• Tag: His
• Form: Multimer consisting of as many as ten non-covalently and covalently linked subunits.
• Bio-activity: Measured by its binding ability in a functional ELISA. Immobilized rhC1q at 5 μg/mL (100 μL/well) can bind rmPentraxin 3 with a linear range of 0.25-15 μg/mL.
• Molecular Mass: Predicted Molecular Mass: 41 kDa (monomer)
  SDS-PAGE: 46 kDa, reducing conditions
• N-terminal Sequence Analysis: Glu18
• Endotoxin: <1.0 EU/μg of the protein by the LAL method.
• Purity: >90%, by SDS-PAGE under reducing conditions and visualized by silver stain
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  12 months from date of receipt, -20 to -70 centigrade as supplied.
  1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
  3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in MOPS, NaCl and CaCl2 with BSA as a carrier protein.
• Reconstitution: Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
• Shipping: The product is shipped at ambient temperature.

Gene Information

• Gene Name: Ptx3 pentraxin related gene [ Mus musculus (house mouse) ]
• Official Symbol: Ptx3
• Synonyms: Ptx3; pentraxin related gene; TSG-14; pentraxin-related protein PTX3; pentaxin related; pentaxin-related protein PTX3; pentraxin 3; tumor necrosis factor-inducible gene 14 protein
• Gene ID: 19288
• mRNA Refseq: NM_008987
• Protein Refseq: NP_033013
• UniProt ID: P48759