Active Recombinant Mouse Sema3a Protein, Fc-tagged
Cat.No. : | Sema3a-01M |
Product Overview : | Recombinant Mouse Semaphorin 3A (Asn21-Lys747: Arg552Ala, Arg554Ala, Arg555Ala, Arg618Ala, Lys619Ala, Lys642Ala, Lys643Ala) with a mouse IgG2A (Glu98-Lys330) Fc tag was expressed in chinese hamster ovary cell line. |
- Specification
- Gene Information
- Related Products
Description : | Enables chemorepellent activity; neuropilin binding activity; and semaphorin receptor binding activity. Involved in several processes, including nervous system development; positive regulation of male gonad development; and ventral trunk neural crest cell migration. Acts upstream of or within several processes, including dichotomous subdivision of terminal units involved in salivary gland branching; generation of neurons; and negative regulation of epithelial cell migration. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; metanephros; and sensory organ. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 16 with or without anosmia. Orthologous to human SEMA3A (semaphorin 3A). |
Source : | CHO |
Species : | Mouse |
Tag : | Fc |
Form : | Disulfide-linked homodimer |
Bio-activity : | Measured by its ability to cause collapse of chick embryonic dorsal root ganglia (DRG) neuron growth cones. 20-60 ng/mL of Recombinant Mouse Semaphorin 3A Fc Chimera causes > 50 % growth cone collapse in the presence 10 ng/mL Recombinant Human beta‑NGF. |
Molecular Mass : | 115-120 kDa, reducing conditions |
N-terminal Sequence Analysis : | Asn21 |
Endotoxin : | < 1.0 EU/μg of the protein by the LAL method. |
Purity : | > 90 % by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. |
Reconstitution : | Reconstitute at 100 μg/mL in PBS containing at least 0.1 % human or bovine serum albumin. |
Shipping : | The product is shipped at ambient temperature. |
Gene Name : | Sema3a sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A [ Mus musculus (house mouse) ] |
Official Symbol : | Sema3a |
Synonyms : | Sema3a; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; SemD; SEMA1; Semad; coll-1; Hsema-I; semaphorin-3A; collapsin-1; sema D; sema III; semaphorin III; semaphorin-D |
Gene ID : | 20346 |
mRNA Refseq : | NM_009152 |
Protein Refseq : | NP_033178 |
UniProt ID : | O08665 |
Products Types
◆ Recombinant Protein | ||
SEMA3A-853H | Recombinant Human SEMA3A Protein, His-tagged | +Inquiry |
SEMA3A-13H | Active Recombinant Human SEMA3A Protein, Met-6-His/Fc-tagged | +Inquiry |
SEMA3A-1901H | Recombinant Human SEMA3A Protein, His-tagged | +Inquiry |
Sema3a-7021M | Recombinant Mouse Sema3a protein(Lys26-Phe546), hFc-tagged | +Inquiry |
SEMA3A-4971R | Recombinant Rat SEMA3A Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
SEMA3A-1770MCL | Recombinant Mouse SEMA3A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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