Angiotensin II Converting Enzyme (ACE2) Activity Assay Kit (Fluorometric)
Cat.No. : | Kit-2210 |
Product Overview : | Angiotensin II converting enzyme (ACE2, EC 3.4.17.23), a zinc-based metalloprotease, is part of the renin-angiotensin system (RAS) that controls the regulation of blood pressure by cleaving the C-terminal dipeptide of Angiotensin II to convert it into Angiotensin 1-7. ACE2 is a receptor of human coronaviruses, such as SARS and HCoV-NL63. It is expressed on the vascular endothelial cells of lung, kidney and heart. ACE2 is a potential therapeutic target for cardiovascular and coronavirus-induced diseases.ACE2 Activity Assay Kit kit will help the research progress in this field. This kit utilizes the ability of an active ACE2 to cleave a synthetic MCA based peptide substrate to release a free fluorophore. The released MCA can be easily quantified using a fluorescence microplate reader. We also provide an ACE2 specific inhibitor that can differentiate the ACE2 activity from other proteolytic activity. The kit can detect as low as 0.4 mU. Our assay kit is simple and can be used in a high-throughput format. |
- Specification
- Gene Information
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Applications : | Detection of ACE2 activity in tissue/cell lysates and enzyme preparations. |
Storage : | -20°C |
Size : | 100 assays |
Products Types
◆ Recombinant Protein | ||
ACE2-1082H | Recombinant Human ACE2 protein(Met1-Ser740), His-tagged, Biotinylated | +Inquiry |
Ace2-033R | Recombinant Rat ACE2 Protein, Fc-tagged | +Inquiry |
ACE2-04H | Recombinant Human ACE2 Protein, Human IgG1 Fc-tagged(C-ter) | +Inquiry |
ACE2-0464H | Recombinant Human ACE2 Protein (M1-S740), Tag Free | +Inquiry |
ACE2-090H | Recombinant Human ACE2 Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
ACE2-887CCL | Recombinant Cynomolgus ACE2 cell lysate | +Inquiry |
ACE2-1851RCL | Recombinant Rat ACE2 cell lysate | +Inquiry |
ACE2-2085MCL | Recombinant Mouse ACE2 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2101 | Angiotensin II Converting Enzyme Inhibitor Screening Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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