CD71 protein-coupled magnetic MicroBeads

• Cat.No.: CD71-491M

Specification

• Species: Human
• Capacity: for 1×10^9 total cells
• Background: The CD71 antigen is also known as the transferrin receptor, which is essential for iron transport into proliferating cells. It is expressed on mesenchymal stromal cells (MSCs) in bone marrow, on activated T and B lymphocytes, macrophages, and on all proliferating cells. It is up-regulated on lymphocytes during proliferative responses to antigens or mitogens but is not expressed on resting lymphocytes. Furthermore, CD71 is present on reticulocytes and erythroid progenitors in fetal liver, cord blood, and peripheral blood, but is downregulated as these cells differentiate into mature erythrocytes.
• Application: Enrichment of fetal early erythroid cells from maternal peripheral blood
  Isolation of hematopoietic precursor cells committed to the erythroid lineage (BFU-E) when used in combination with the CD34 MultiSort Kit